IRACROSS - CROSS LINKED HYALURONIC ACID WITH DVS FOR INTRA-ARTICULAR INJECTIONS

An injectable, non-pyrogenic, reabsorbable Medical Device containing cross linked Hyaluronic Acid of non-animal origin, produced via bacterial fermentation. The product presents itself as a colorless gel contained in a pre-filled, graduated, disposable and sterile glass syringe with a Luer Lok adapter.

ADVANTAGES:

·        Hypersensivity reactions are minimized by high purity, low concentration of nucleic acids, proteins and endotoxins (≤ 0,5 EU/ml much lower than the limits of toleration indicated by European Pharmacopoeia for injectables)

·        Higher concentration of cross linked Hyaluronic Acid compared to other fillers on the market

 

DIRECTIONS:

Intra-articular treatment for pain and/or reduced mobility due to traumatic or degenerative deformities of the knee or synovial joints.

 
ACTION:

Hyaluronic Acid promotes the viscoelastic properties of the synovial fluid, promoting lubrication. In degenerative joint pathologies such as chronic primary osteoarthritis, synovial fluid has a reduced viscosity, decreasing the joint’s shock absorption ability and lubrication.

Intra-articular injections with Hyaluronic Acid promote joint repair by acting on chondrocyte growth and metabolism, stimulating the production of endogenous Hyaluronic Acid, proteoglycan and collagen synthesis, inhibiting expression of chondrolytic enzymes as well as decreasing the inflammatory responses. As a result, overall mobility and joint function are improved, promoting major viscosity of the synovial fluid, thereby reducing mechanical joint overload and painful syntoms.

 

PROTOCOLS OF USE:

Intra-articular injections must be performed uniquely by qualified medical personnel.

Inject into the joint cavity using a spinal needle (between 18G and 21G).