Isolators for High Potency API Containment: Toxic Applications

Operations around chemical reactors, filters, centrifuges and dryers need to be executed under containment conditions when handling HPAPI or intermediates.

FPS Mechanical Mills are designed to reduce agglomerates of pharmaceutical, chemical and food products down to fine size. The system includes hygienic design mill housing with interchangeable rotor and stator. FPS Mechanical Mills available are: PinMill-100, PinMill-200, HammerMill-100 and H...

FPS is proud to introduce the first isolator with integrated vocal commands.

Containment systems allow the operator to handle highly toxic (HAPI and HPAPI) or sterile powders safely and efficiently. One of the main processes performed inside the isolator is the handling of powders...

The PilotMill series is able to meet the request for laboratory needs and small production batch sizes (from 3g to 100kg).

The ProMill series is engineered to encounter the request from production facilities, where large volumes are processed in a flexible and efficient operation.

The R&D Jet Mill series is engineered to meet the requirements of R&D labs, where new product are developed and micronization process is requested on small quantities (from minimum 10mg to 100g).

FPS sterile containment systems maintain a sterile environment around processes, requiring minimal space and eliminating the necessity for sterile cleanrooms.
Our custom isolators are meticulously engineered to meet the highest pharmaceutical standards, ensuring impeccable sterile c...

The latest challenge was to design a multi-purpose isolator used to micronize down to a few microns covering a wide range of batch size and assuring a Containment Performance Target (CPT) of 50ng/m3. Inside the isolator, a 4”, 8” or 12” jet mill can be used. To achieve this, a 9-chamber isolator has been d...

Benefits of FPS Solution:
• FPS provides both the containment system and the micronization unit • All components of the micronization units are designed to be connected to the Sterilization In Place line • Decontamination cycles specifically developed to guarantee an aseptic environment...

FPS recently designed and manufactured an isolator to dispense up to 100kg of potent sterile API in specific containers to be connected to the process equipment.

During the discovery phase of the customer needs, the various stages of the process were analyzed:
1) introduction of th...

Operations around chemical reactors, filters, centrifuges and dryers need to be executed under containment conditions when handling HPAPI or intermediates. Depending on process equipment dimensions, the isolator system is designed fully enclosing the equipment or only the parts where product transfer occur...

ANFD barrier isolator allows high active product discharge from filter dryers and heel removal for total product recovery. The isolator is directly supported by the filter dryer; installed on a  flange fixed on the discharge hatch.Activities are performed by working through glove ports installed on front ...

"We are highly specialised in the design and manufacture of custom isolators for potent active ingredients and sterile solutions. Our collaborative design process includes creating full-scale mock-ups to validate ergonomics and functionality, ensuring tailored solutions for each client." - Paolo Barilli - FPS Pharma Process Engineer

Let's explore the FPS Pharma Engineering Process.

Explore FPS’ micronization and jet milling systems. Achieve exact PSD targets, enhanced bioavailability, and cGMP compliance for superior formulations.

At FPS Pharma, the creation of custom isolators is more than a process; it’s a journey of collaboration, innovation, and precision.
From the moment customer needs are reviewed to the final testing phase, every step of the design and production process is meticulously carried out at our Fiorenzuola d’Arda (PC) plant.

Central to this journey is the mock-up phase—a pivotal step that brings the isolator to life at full scale.
FPS Pharma strongly encourages the use of mock-ups, allowing customers to physically interact with the isolator and assess its ergonomics and functionality before final production.

Discover FPS’ isolators for aseptic processing. Ensure sterility, safety, and cGMP compliance, tailored to your production requirements and plant space.

Discover how to optimize pharmaceutical HPAPI processing with FPS’ advanced containment isolators. Ensure top-tier safety, compliance, and efficiency.

Discover GloveXpert: the ultimate glove leak tester for pharmaceutical isolators. Fast, accurate, ergonomic, and lightweight. Visit our booth to test it!