New controlled nucleation resource center

SP Scientifc's ControLyo Central is a suite of online resources to help freeze dried parenterals manufacturers.

Using an animated video format, SP Scientific introduces the science of ControLyo Technology, the process of implementation, and its potential financial benefits to businesses through factors such as shorter cycle times, reduced waste, and improved product quality.

The video shows how staff at an illustrative pharmaceutical company are faced with slowed production due to lyophilization problems including variations in moisture levels, homogeneity and yield for a new injectable drug. The characters introduce ControLyo Technology and explain in simple terms how the technology affords precise control over the point of freezing during the lyophilization process - a critical factor affecting variability within a batch. Further they describe how ControLyo can reduce cycle time, virtually eliminate waste, improve product quality without requiring any formulation change and maintain sterility. Finally, the cost analysis demonstrates a typical 4-month payback on investment in ControLyo Technology in their production environment.

Additional videos within ControLyo Central include footage of traditional lyophilization versus ControLyo Technology, and 'in action' applications involving lyophilization in both vials and syringes. Visitors to the site will find research publications and supporting literature with Spatially modulated illumination (SMI) microscopy images to further understand this innovative freeze drying breakthrough and its impact on product quality and production efficiencies.