New presentations at ATS 2016 reinforce OFEV efficacy, safety and tolerability across range of patients with IPF
A new analysis of Phase III INPULSIS trials reinforces OFEV's slowing of disease progression in a composite endpoint involving lung function decline (FVC decrease >10%) and death.
New analyses presented at the American Thoracic Society's 2016 annual conference (ATS 2016) further add to the efficacy and safety profile of OFEV (nintedanib) in idiopathic pulmonary fibrosis (IPF). In total, Boehringer Ingelheim presented 12 IPF-related abstracts at ATS, including further analyses of the INPULSIS trials, which add to the growing body of evidence reinforcing the clinical benefit of OFEV across a range of patients by showing that
"IPF progression is variable and unpredictable, but, over time, the lung function of patients gradually and irreversibly declines," said Imre Noth, Professor of Medicine and Director of the Interstitial Lung Disease Program at the University of Chicago. "Ongoing analyses of the Phase III INPULSIS trials along with real-world data provide additional support for the safety and efficacy of treatment with OFEV. As slowing disease progression is an important treatment goal, these data provide support for the benefit of IPF patients regardless of disease severity."
The new analyses from the pooled Phase III INPULSIS trials showed that:
"Boehringer Ingelheim is committed to furthering science that addresses the unmet needs of people with rare diseases where limited treatments exist," said Danny McBryan, vice president, Clinical Development and Medical Affairs, Respiratory, Boehringer Ingelheim Pharmaceuticals, Inc. "Already, more than 10,000 patients worldwide have received treatment with OFEV to date, and we're continually working to advance the understanding of IPF through our clinical trial program and ongoing research of OFEV in the real-world clinical setting."
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