Quark Reports Results from Diabetic Macular Oedema Drug Study
After 12 months of treatment with PF-04523655, a dose-dependent improvement in visual acuity was observed, with the best results achieved at the 3mg dose level.
Quark Pharmaceuticals has announced results from a Phase II trial evaluating the safety and efficacy of PF-04523655 (RTP801I-14) in patients with diabetic macular oedema. Interim results at 12 months revealed that there were no drug-related serious adverse events.
After 12 months of treatment with PF-04523655, a dose-dependent improvement in visual acuity was observed, with the best results achieved at the 3mg dose level.
The prospective and randomised trial enrolled 184 patients who received one of three dose levels of PF-04523655 (0.4mg, 1mg, and 3mg) or laser photocoagulation control, the current standard of care.
The endpoint of the study was
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