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24 May 2011

Study Finds Gene Warning of Alzheimer's before Symptoms Onset

A gene allele that increases the risk of Alzheimer's disease starts to damage the brain 50 years before symptoms of the disease appear, a new study says.

According to a new study by the University of California, Los Angeles (UCLA) researchers, clusterin, or CLU, one of a handful of genes that is known to carry a heightened risk of Alzheimer's, begins to attack human brain a half-century before Alzheimer's symptoms appear.


UCLA professor Paul Thompson and his team found that the C-allele of the CLU gene, or one of two or more forms of the gene, hinders development of myelin, which protects the neuron's axons in the brain. This makes the brain more vulnerable to Alzheimer's later in life. But the da

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