Type 1 Diabetes Vaccine Fails Trial

The researchers believe the vaccine could be used as part of a combination therapy to recent-onset type 1 diabetes patients.

A vaccine against the progression of type 1 diabetes has failed to elicit a response in a trial presented at an American Diabetes Association meeting. The trial was conducted by the Diabetes Research Institute at the University of Miami Millar School of Medicine in Florida.

The researchers believe the vaccine could be used as part of a combination therapy to recent-onset type 1 diabetes patients.

The vaccine tested a hypothesis: scientists could target the same antigen as type 2 diabetes for type 1, glutamic acid decarboxylase (GAD). According to data from the 145 patient study, all three groups in the study--who received three injections of the vaccine, two vaccine doses and one alum, or all alums as a control--achieved similar beta cell function decline.