14C Radiolabelling

14C Radiolabelling
Product Description

QC and analytical support, including method development and validation, method transfer and radiolabelling stability studies

With our extensive experience in the synthesis and analysis of stable and 14C isotope labelled compounds – from drug discovery through to launch. We can label any compound at any stage, including small molecules, peptides, and antibody drug conjugates.

14C is the radioisotope of choice in preclinical and clinical ADME studies. 14C avoids the challenges encountered with tritium labelling, including label exchange and the loss of label due to radioactive decay.

2H, 13C and 15N stable labels are routinely used to prepare stable labelled versions of APIs. Multiple labels are typically incorporated to ensure complete mass resolution from the unlabelled API.

Isotopic labelling imposes many synthetic challenges beyond those found in normal chemical synthesis. When the isotope is radioactive, this becomes even more demanding. That’s why we offer advice on the most appropriate label position for your molecule, including feasibility and metabolic stability.

We can provide a complete suite of solutions for your radiolabelling needs, including:
- Non-GMP and GMP Stable Labelling
- Facilities and Equipment
- ADC Labelling

- QC and analytical support, including method development and validation, method transfer and stability studies
- Storage and Re-purification


We are MHRA certified for 14C IMP and GMP compliance and we are fully equipped to deliver an industry-leading, cost-effective radiolabelling service.

Almac Group

  • GB
  • 2015
    On CPHI since
  • 4
    Certificates
  • 5000+
    Employees
Company types
CMO/CDMO
Contract Service
Packaging supplier/manufacturer
Primary activities
Analytical Services
API Producer
Biopharmaceutical
Chemical Development
Contract Manufacturer
Custom Manufacturing/Custom Synthesis
Fine Chemicals Company
Intermediates Manufacturer
Laboratory Services
Other
Packaging & drug delivery
Supply Chain
Transport/Logistics/Distribution

Almac Group

  • GB
  • 2015
    On CPHI since
  • 4
    Certificates
  • 5000+
    Employees
Company types
CMO/CDMO
Contract Service
Packaging supplier/manufacturer
Primary activities
Analytical Services
API Producer
Biopharmaceutical
Chemical Development
Contract Manufacturer
Custom Manufacturing/Custom Synthesis
Fine Chemicals Company
Intermediates Manufacturer
Laboratory Services
Other
Packaging & drug delivery
Supply Chain
Transport/Logistics/Distribution

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