Our Biocatalysis Group
Consisting of computational, molecular and micro biologists, enzymologists, organic chemists and analysts, the group has demonstrated expertise in gene identification, expression, enzyme evolution, fermentation, enzyme production and biotransformation scale-up. Expertise ranges from enzyme production to the synthesis of complex chiral APIs from mg-tonne scale.
Our team is closely linked to the process chemistry and manufacturing chemistry groups, where enzyme discovery and development is integrated with screening and route definition. Each member of the team brings expertise to complex processes procedures and can rapidly implement an enzymatic process to significantly improve the yield and timelines of a multi-step synthesis.
In addition, Almac has recently acquired Arran Chemical Company which significantly increases our scale (a range of reactors up to 6,300L and total capacity of up to 45m3). The new combined business will integrate Biocatalysis technology with large scale intermediates manufacture. The bespoke facility offers a full range of scales including kg lab, multi-purpose pilot plant and manufacturing plant.
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