Shandong Binzhou Zhiyuan Biotechnology Co., Ltd

Company Profile Shandong Binzhou Zhiyuan Biotechnology Co., Ltd. specializes in the R&D, production and application of cyclodextrin derivatives, cyclodextrin inclusion complexes and chitosan derivatives. With an annual production capacity of 10,000 tons, the company maintains a sound management system and a professional R&D team. Product Features Zhiyuan Biotechnology offers over 70 product varieties across six major categories: cyclodextrin derivatives, cyclodextrin inclusion complexes, chitosan derivatives, cyclodextrin reagents, cosmetic raw materials, and customized inclusion complexes. Its products are widely used in pharmaceutical excipients, cosmetic ingredients, functional foods, flavors and fragrances, new materials, medical dressings, natural pigments, contact lens care solutions, and in vitro diagnostic reagents. Quality Assurance System Zhiyuan Biotechnology has obtained certifications for ISO9001:2015 (Quality Management), ISO14001:2015 (Environmental Management), ISO45001:2018 (Occupational Health and Safety), as well as Kosher and Halal certifications. The company boasts a 2,000 m² high-standard GMP workshop and is equipped with over 50 sets of internationally advanced testing instruments, including Thermo Fisher ion chromatographs, Beckman capillary electrophoresis systems, Shimadzu gas chromatographs, and liquid chromatographs, enabling full in-house testing from raw materials to finished products to ensure stable and reliable product quality. Scientific Research and Innovation Zhiyuan Biotechnology collaborates with Shandong University, Nankai University, China Pharmaceutical University, and Fudan University to establish the Cyclodextrin Application Research Center, the Cyclodextrin Collaborative Innovation Center, and a joint cyclodextrin laboratory. The company has built five provincial and municipal R&D platforms, including an application R&D center built to world-class standards, and has successively undertaken multiple major national and provincial scientific research projects, Qualifications and Honors The company's core products have obtained globally recognized certifications: Hydroxypropyl Betadex, Betadex sulfobutyl ether sodium, Hydroxypropyl Gamma cyclodextrin, Methyl Beta cyclodextrin, and Hydroxypropyl Chitosan have all completed CDE filing and registration. Among them, Hydroxypropyl Betadex, Betadex sulfobutyl ether sodium and Hydroxypropyl Gamma cyclodextrin have successfully passed FDA filing and registration.Hydroxypropyl Betadex, Betadex sulfobutyl ether sodium have obtained EDQM-CEP certificates. The new cosmetic raw material — hyperbranched cyclodextrin — has obtained the national cosmetic new raw material filing with the registration number 20250095. Key Partners All of Zhiyuan Biotechnology's products have independent intellectual property rights. With outstanding quality and technical strength, the company's products are exported to Europe, the United States, Japan, South Korea, India, Pakistan, South America, the Middle East, and other countries and regions, earning high recognition and praise.