Biodue SpA was founded in 1986 by Sion Fulvio Benedetti and develops manufactures and distributes Medical devices, Skin cosmetics and Dietary supplements (in solid and liquid forms). In 2018, Biodue reached a turnover above 41 Million Euros and about 160 employees. The plants and warehouses cover almost 21.000 square meters and all of them are located in an industrial area near Florence.

The company has two main core businesses: the Industrial division, focused on contract manufacturing and the Brand division, focused on the commercialization and promotion of the company’s own products. Within the Brad division, there are three Brands: Selerbe’s portfolio, based on herbal products, promoted to pharmacies; Pharcos’ portfolio, including medical devices, food supplements and cosmetics, promoted to dermatologists and Biofta’s portfolio, including medical devices and food supplements, promoted to oculists/ophthalmologists.

The company commercialize and promote its own products directly in Italy and through JVs in US and Latam; the company has in place agreements with local/regional partners in several geographic areas not covered directly.

The company has recently developed and patented in EU and US an innovative technology - RewCap® - applicable to vaginal douche, mono-dose food supplements, drops food supplements and mono-dose medical devices.

The company is registered under EC Regulation number 852/2004 and under GMP (Good Manufacturing Practices) certification. The company is also registered with the US Food and Drug Administration (U.S. FDA Registration no.10725095718).  The Company received the ISO 13485 certification for the development, manufacturing and production of medical devices.  


  • IT
  • 2015
    On CPhI since
Meet us at

CPhI Worldwide 2021

Fiera Milano, Milan, Italy
9-11 November 2021

Products from BIODUE SPA

  • Corneial gocce 10 ml - eye drops

    Product Corneial gocce 10 ml - eye drops

    Corneial® gocce is a Medical Device class IIa sterile, an adjuvant solution for the prevention of red and tired eyes. Eliminate inflammation and promote re-epithelialization. Protects the corneal epithelim and improves ocular disconfort. Suitable for anyone suffering from dry eyes, poor tear formation, as well as redness caused by external agents and using contact lenses. Infuse 1-2 drops of the product directly into the eyes whenever you feel the need, even several times a day.Contains: Glycerophosphoinositol (GPI), PHMB, Hyaluronic acid 0,2%, natural extracts.Supported by a clinical study on 150 patients.
  • Cicaialo Gel Wounds

    Product Cicaialo Gel Wounds

    Acts by protecting the wound that has damaged the derma creating an optimalenvironment for repairing and protecting processes, at the same time, the area fromexternal agents of physical (rubbing) and bacterial nature.Takes coadjuvant action in the repairing process of the tissue in the case of:- Irritations and redness;- Post peeling, depilation and laser operations;- Newborn navel;- Superficial injuries: cracks, grains, grazes, abrasions, minor burns, superficial cuts;- Deep injuries: surgical wounds, bedsores, ulcers.MEDICALDEVICE 2BWith clinicalevidenceCicaialoGel WoundsGel based on Hyaluronic acid, Aloe Vera and Jojoba Oilfrom Organic agriculture adjuvant for Wounds, burns andIrritations.INSTRUCTIONS FOR USE:Wash hands before use. After cleaning and disinfecting thearea, apply a thin layer of gel directly on the treated area, gentlymassaging until complete absorption. Close the tubeafter use. Apply 2 times a day until the remission of thesymptoms. Treatment should not exceed 30 days.If the symptom persists, contact your doctor or pharmacist.Can be applied also on DEEP WOUNDSEVEN FOR POST PARTUM WOUNDS AS CESAREO OR EPISIOTOMY CUTINDICATED ALSO FOR NEWBORN NAVEL TREATMENT OR IRRITATIONOR REDNESS FROM DIAPERNEWSCOMPOSIZIONE:Aloe Vera, Sodio Ialuronato, Acrylates/C10 - 30 alkyl Acrylate Crosspolymer,Olio Jojoba*, Polivinilpirrolidone (PVP), Sodio idrato perle, Benzl Alcohol, GlycerylCaprylate, Glyceryl Undecylenate, Aqua.(*: da agricoltura biologica)PACKAGING: tube of 25 g Public price in Italy: 11,50 €
  • Fotoker - 50 ml

    Product Fotoker - 50 ml

    Fotoker is a Medical Device class I. Leaves a protective film on the skin in a way that can prevent DNA damage arising due to UV rays, which predispose toward various forms of skin cancer, thanks to the presence of Photolyase and Tripeptide. Control the actinic damage. MOLECULAR SURGERY WITH TOPICAL DNA REPAIR ENZYMES FOR MAINTAINING THE GENOME STABILITY PHOTOLYASE - IMMEDIATE REPAIR OF THE ACUTE DAMAGE. Supported by a clinical study and by an observational study on 120 patient.
  • ALTIAL PLUS 10 ml - eye drops

    Product ALTIAL PLUS 10 ml - eye drops

    ALTIAL® Plus is an ophthalmic lubricating solution based on highly cross-linked hyaluronic acid, formulated for the treatment of ocular discomfort deriving from: prolonged exposure to sunlight; permanence in air-conditioned rooms; prolonged use of computers, video terminals, television; redness caused by external agents; use of contact lenses.Highly cross-linked HA has a greater stability (the "link" structure protects from the degradation of the enzyme hyaluronidase) and a longer effect in situ in comparaison to HA.  Instill directly in the eye, when the need is felt, 1-2 drops of product, even several times a day.


    Food supplements: oral solutions in bottles, drops, spray, sachet, tablets, capsules, monophasic and biphasic vials Medical devices: spray, vaginal cleanser and ovules, gel, cream, topical products
  • OFTALDERM SCAR - 15 ml

    Product OFTALDERM SCAR - 15 ml

    Oftalderm scar is a Medical Device class II b.  Adjuvant for healing wounds, burns and irritations.
    Indications: • Irritations and redness (Blepharitis, eczema); • Post dermatological treatments and cosmetic surgery; • Superficial injuries: cracks, scratches, bruises, abrasions, minor burns, superficial cuts; • Deep injuries: surgical wounds, ulcers.

    It contains: • Hyaluronic acid "HIGH MOLECULAR WEIGHT" : generates a protective film that protects, moisturizes and regenerates the injured dermis 
     • Aloe Vera (Aloe Bardensis Miller) antibacterial, antiseptic and anti-inflammatory that favors wound repair processes, signs and blemishes of the skin • Jojoba Oil (Simmondsia chinensis) esterified wax mixture that re-establishes a correct hydrolipidic film on the skin  
    Clinical data available!
  • Fitointimo - Vaginal douche

    Product Fitointimo - Vaginal douche

    • MEDICAL DEVICE • Rose Parfume Fitointimo Vaginal douche, is a Medical device composed of a mix of probiotic powder contained in an innovative reservoir-cap, fitted on a bottle filled with a solution of Aloe Vera and Tea Tree Oil. Powder and solution are mixed before use thanks to the practical patented closure system Rew Cap™. INDICATIONS: Restoration of the physiological vaginal conditions (vaginal bacterial flora and pH re-equilibrium) that may have been altered as a consequence of infections, prolonged antibiotic therapies and/or other feminine genital pathologies. Coadjutant during the treatment or the prevention of bacterial vaginitis and vaginosis. Protective/lenitive during irritation of vaginal mucosa. COMPOSITION: In the cap: Lactobacillus acidophilus, Lactobacillus rhamnosus, Hydrated silica, Micronized silica, Talc, Magnesium stearate, Maltodextrin. In the bottle: Melaleuca Alternifolia (Tea Tree oil) oil, Aloe Vera (Aloe Barbadensis), Lactic Acid, Polisorbate 20, Sodium Benzoate, Potassium Sorbate, Parfum, Water. Packet: 1x100 ml with REWCAP® and 1 applicatorPacket: 4x100 ml with REWCAP® and 4 applicators 
  • Fitointimo - Vaginal Gel

    Product Fitointimo - Vaginal Gel

     • MEDICAL DEVICE• Rose parfume INDICATIONS: Fitointimo Gel is adjuvant in the treatment of vaginal mucosa affections of bacterial origin (such as for example Vulvovaginitis) or fungal infection (such as candida) which determine dryness, redness, itching and burning. The product creates a protective barrier on the vaginal mucosa which gives immediate relief with deep soothing and lubricating actions. The product contributes to the preservation and stabilization of thephysiological pH and promoting the wealth of the vaginal mucosa. COMPOSITION: Aloe Barbadensis, Grapefruit Seed Dry Extract, Salvia officinalis Glycolic extract, Salvia Officinalis essential oil, Sodium Hyaluronate, Polycarbophil,Hydroxyethylcellulose, Lactic acid, Disodium EDTA, Sodium Hydroxide,Sodium dehydroacetate, Imidazolidinyl urea, Parfum, Water. Packet: Tube 40 ml + 6 cannulas
  • Fitointimo - Vaginal Ovules

    Product Fitointimo - Vaginal Ovules

    MEDICAL DEVICE INDICATIONS: Fitointimo Vaginal Ovules is an adjuvant in the treatmentand prevention of vaginal mucosa diseases due to bacteria (as vulvovaginitis) or to fungal infection (such as Candida). Indicated to relieve burning, itching and redness. Also useful as a preventive treatment in patients with frequent infections.COMPOSITION: CANDIResolve™ (Vegetal complex with polisaccarides from Aloe Barbadensis, Salvia Officinalis essential oil, Tea tree oil tit.30% in terpen-4-olo, Grapefruit Seed Dry Extract), Lactic acid,Mixture of triglycerides. Packet : 10 ovules of 2 g


    Medical device 50 ml tube with 1 applicator Cream Without PEG, PARABENI, PHENOXYETHANOL, EDTA, SLS, SLES Adjuvant in the treatment of hemorrhoid states, useful to Relief to the symptoms of itching and burning. The action of FitoPROCT is obtained through PROCTOResolve ™, (plant complex Based on polyphenols from a selection of Oliv’s leaves, variety Frantoio, Leccino and Moraiolo, high Molecular Weight of the Aloe Vera polysaccharides and tannins(From Chestnut) enriched with VegetalHYALO ™ (hyaluronic acid of Vegetable origin) and vegetable oils, calming the irritation by protecting the mucosa. The hypericum Oil is obtained by cold squeezing of the fresh flowers of Hypericum Perforatum. COMPOSITION PROCTOResolve ™ (vegetable complex based on Aloe Vera polysaccharides,Olive Oil Polyphenols, Chestnut Tannins), VegetalHYALO ™ (Hyaluronic Acid Of vegetable origin), Iperic Oil and Sweet Almond Oil, Glutamate Tetrasodium Diacetate, Sodium Methylglycate Hydroxide, Sodium Hydrate, Vitamin E Acetate, Glycerin, Carbomer, Polyglyceril-3 Rice Branate, Water. * From organic farming DOSAGE Apply the cream as needed, whenever possible after each evacuation After careful and gentle washing) In order to obtain a preventive treatment against the irritation due to rubbing, the treatment can be applied before bowel evacuation taking care to apply the product even afterwards. The cream can e applied with or without the applicator. You can repeat it several times a day, even for prolonged periods. MODE OF USE For an outdoor application, spread and gently massage Anal and perianal area For an internal application, use the appropriate endoretic cannula, following the instruction below. 1. Drill the hose using the plug stopper, 2. Remove the dispenser cap, 3. lubricate the applicator by leaking a small amount of product, 4. screw the rectal applicator, 5. Insert into the rectum, squeeze the tube until a sufficient quantity of the product is introduced 6. After use clean the applicator with hot water and soap and close the applicator with the cap.  STORAGE Keep the container tightly closed in a dry and well-ventilated place and away from the heat sources. Do not use the product if the packaging isn’t entire. Don’t use the product after the expiration date. The expiration date refers to the product that is intact and properly stored. WARNINGS The product is for rectal use. Do not swallow. Do not use in case of hypersensitivity and of incompatibility with any component of the product. Although the tests didn’t evidenced phenomena of sensitizzation, in the event that these phenomena occur  It is advisable to discontinue treatment and consult the doctor. Keep out of reach of children. Do not use in the event of injury. For Pregnancy and, in the case of concurrent drug therapies, Consult your doctor / pharmacist. The product is not intended for pediatric use. SIDE EFFECTS There are no known or expected the side effects related to the use of the product. The tests performed on the product to this date, did not show phenomena of Sensitization or other side effects. In the event of persistent annoyances consult your doctor or pharmacist. PACKAGE 1 50 ml tube with 1 applicator.
  • CITINERV - 14 sachets 4,6 g

    Product CITINERV - 14 sachets 4,6 g

    CITINERV is a Food Supplement for optic neuropathy and can contribute to the efficiency of the nervous system function.CITINERV is indicated for glaucoma, amblyopia and more, it repairs, connects and protects neuronal cells. CITINERV contains: - CITICOLINE- 800 mg KYOWA QUALITY: NEUROPROTECTIVE/NEUROSTRUCTURAL/NEUROMODULATORY ACTION - NERVONIC ACID: ANTIOXIDANT, NEUROTROPHIC/PROTECTIVE, ESSENTIAL FOR MYELIN SHEATH'S BIOSYNTHESIS - GROUP B VITAMINS  CLINICAL DATA available on the product!
  • VITREOIAL - 20 sachets 4 g

    Product VITREOIAL - 20 sachets 4 g

    VITREOIAL is a Food Supplement for VITREOUS BODY ALTERATIONS. Reintegrates, rehydrates and protects the vitreous matrix.VITREOIAL is Gluten Free and NON effervescent.VITREOIAL is indicated for Myodesopsia/Phosphenes, Retinal detachment, Vitreous hemorrhage, Hypokalemia and more. VITREOIAL contains:  - Micronized HA/ Aminoacids: structiral reintegration of the vitreal matrix. - Liposomial Glutathione: enhanced antioxidant activity  - Vitamins C and E: antioxidant activity - Magnesium/Potassium: hydrosaline balance  CLINICAL DATA available on the product!

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