Fatty Acids Side Chains

JenKem Technology offers large scale GMP manufacture of premium fatty acid side chain products for drug modification, with batch size of 10kg-100kg, with high purity and good lot-to-lot reproducibility. Fatty acid side chains are known to aid in improving patient compliance with increased half-life for Glucagon-like peptide-1 (GLP-1) receptor agonists, which are extensively used in the treatment of type II diabetes and obesity. For example, several drug entities such as tirzepatide, somapacitan, or semaglutide, are modified to incorporate fatty acid side-chains.

Fatty Acid Side Chain – related products and services offered by JenKem Technology:

• Fatty Acid Side-Chain Custom Synthesis• Customized Molecular Coupling Services 
• Characterization of Modified Polypeptide(s) and their Catabolites
• Quality Studies Related to Clinical Studies