IOI PRODUCT SPOTLIGHTS: MIGLYOL® 812 N & IMWITOR® 742

Nanoemulsions offer a promising method for dissolving and delivering active ingredients, especially BCS classes II and IV, in relevant quantities. IMWITOR® 375 opens up new possibilities to meet these current efficacy requirements. Several case studies have shown how our product can be used in nanoemulsions and what concrete advantages result from this.

CAPSULE INGREDIENTS FOR ALL REGULATORY SCOPES At IOI Oleo, we combine the expertise of two crucial fields: the phar maceutical and nutritional sectors. This enables us to seamlessly offer our partners the best selection of ingredients for every regulatory sco pe. Whether it’s about developing medicinal capsules with the highest efficacy and safety or nutritional supplements that promote health and well-being – we are your reliable partner. Discover how our integrated expertise can elevate your your products to the next level.

When a challenge becomes an opportunity

In the world of pharmaceutical development, there is a constantly growing hurdle: more and more innovative active ingredients are poorly soluble in water or have a low permeability – and are therefore difficult for the human body to absorb. The result? Active ingredients with high therapeutic potential cannot achieve their therapeutic goal. But this is precisely where the newly developed group of excipients, the innovative lipid-based polyglycerol esters, offers new possibilities in the development of formulations.

Protecting farm animals and pets from parasites is a key part of modern veterinary medicine. Pour-on formulations, where a medication is applied directly to the skin or fur, are especially popular because they’re easy to use and stress-free.

Lipid-based excipients for veterinary formulations Our specialties for veterinary applications are used for companion as well as for - farm animals in Injectables 
- SC and IM Infusions 
- IV Oral (e.g. paste, drench) 
- Pour-on / Spot-on formulations 
- Tick and flea collars

Since its first market introduction WITEPSOL® has become the synonym for hard fats and their use as drug delivery systems in ovules and suppositories. With this legacy comes great responsibility that the em ployees of IOI Oleo are aspiring to meet and exceed on a daily basis. 

Our brands – IMWITOR®️, MIGLYOL®️, SOFTIGEN®️, SOFTISAN®️, DYNASAN®️ and WITEPSOL®️ – stand for consistent quality, outstanding performance, and tangible benefits in the final formulation. With a legacy dating back to the 1950s at the former Chemische Werke Witten, IOI Oleo GmbH has built a reputation for excellence in the production of high purity, plant based esters. These multifunctional ingredients serve as emollients, emulsifiers, and more— contributing directly to the quality and safety of pharmaceutical products. Our commitment to purity and safety is reflected in our robust regulatory framework and certifications. We operate under cGMP regulations at our Witten facility, which is regularly inspected by the German Health Authority. Depending on the product, raw materials can be derived from up to 100% plant-based sources. 

Lipid-based excipients made in Germany, manufactured in our EU GMP-certified and US FDA cGMP inspected production facility

DYNASAN® Purified monoacid triglycerides 
IMWITOR® Highly functionalized lipids for drug delivery systems 
MIGLYOL® Reference-quality C8-C 10 esters for pharma formulations SOFTIGEN® Compendial liquid solubilizer 
SOFTISAN® Specialties for topical and oral applications 
WITEPSOL® Benchmark hard fats for suppositories and ovules

Expanding the legacy of WITEPSOL® hard fats as the benchmark for suppositories and ovules, IOI Oleo GmbH introduces LipoGalen® 144 as innovative base for ovules, suppositories and dermal formulations.