PEG Products Catalog

JenKem Technology offers large scale GMP manufacture of premium fatty acid side chain products for drug modification, with batch size of 10kg-100kg, with high purity and good lot-to-lot reproducibility. Fatty acid side chains are known to aid in improving patient compliance with increased half-life for Glucagon-like peptide-1 (GLP-1) receptor agonists, which are extensively used in the treatment of type II diabetes and obesity. For example, several drug entities such as tirzepatide, somapacitan, or semaglutide, are modified to incorporate fatty acid side-chains.

JenKem Technology provides large scale GMP manufacture of monodisperse (discrete) PEG linkers for ADCs and for targeted protein degraders (TPD), including PROTACs, DACs, and LYTACs.

We offer a competitive price for kilogram-scale manufacture for our high-purity monodisperse PROTAC PEG linkers with various active groups, E3 ligase ligands, and E3 ligase ligand-linker conjugates, please contact us at [email protected] for a quotation.

JenKem Technology provides large scale GMP manufacture of PEG-lipids, lipids, PEG intermediates for lipid nanoparticles, along with innovative lipid nanoparticle (LNP) formulation services for selective delivery of mRNA and siRNA therapeutics.

Large scale GMP manufacture of lipids (cationic lipids, ionizable lipids, PEG lipids, phospholipids, helper lipids, SORT lipids, and others made-to-order)Development services for innovative lipids (i.e., JK-0315-CA, JK-102-CA, JK-0039, JK-0005), including lipid process development, quality research, CDE/DMF applications. Several China CDE applications and US FDA DMFs already filed for several LNP excipients
Lipid nanoparticles (LNP) formulation development, such as our innovative 3-component LNPs and 5-component LNPs for selective organ targeting
Lipid nanoparticle (LNP) encapsulation services for development of RNA therapeutics
Analytical testing services for Lipid nanoparticles (LNPs), RNA, and LNP-RNA