Nonproprietary
Names:
Cellacefate, Cellulosi acetas
Phthalas, Cellulose Acetate Phthalate
Synonyms:
Acetyl phthalyl cellulose; CAP;
Cellacefate;
Cellulose acetate
1,2-benzenedicarboxylate; cellulose acetate hydrogen phthalate;
Cellulose acetate monophthalate; Cellulose
acetophthalate; Cellulose acetylphthalate
Cellulose
acetate phthalate (CAP) is used as an enteric film coating material, or as a
matrix binder for tablets and capsules.Such coatings resist prolonged contact
with the strongly acidic gastric fluid, but dissolve in the mildly acidic or
neutral intestinal environment.
Cellulose
acetate phthalate is commonly applied to solid-dosage forms either by coating
from organic or aqueous solvent systems, or by direct compression.
Concentrations generally used are 0.5–9.0% of the core weight. The addition of
plasticizers improves the water resistance of this coating material, and
formulations us
IN