CGMP (±)-Cloprostenol (sodium salt) 

(+)-Cloprostenol is the active enantiomer of Cloprostenol. Cloprostenol is used in veterinary medicine as a luteolytic agent for the induction of estrus and the treatment of reproductive disorders in cattle, swine, and horses. The ASMF for (+)-Cloprostenol (sodium salt) is on file in several EU member states.

Alprostadil is a vasodilator, and finds clinical use in treating erectile dysfunction, in improving blood flow in peripheral vascular disease, and in maintaining coronary circulation in neonates with vascular anomalies. The DMF for Alprostadil is on file with the US FDA, Canada, India, in many EU member st...

Bimatoprost is a potent FP receptor agonist that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma. The DMF is on file with the US FDA, Canada, and in several EU member states.

Epoprostenol is a potent vasodilator and antiplatelet substance with a very short physiologic half-life. It is used for the treatment of pulmonary hypertension. The DMF for Epoprostenol Sodium Salt is on file with the US FDA, Canada, Japan, Australia, and several EU member states.

ANN ARBOR, MI, SEPTEMBER 12, 2023—Cayman Chemical, a world leader in the manufacture of prostaglandins for both research use and as active pharmaceutical ingredients (APIs), has been granted a Certification of Suitability to the monographs of the European Pharmacopoeia (CEP) by the European Directorate for the Quality of Medicines and HealthCare (EDQM) for its latanoprost API, effective August 28th, 2023. Cayman Chemical is the first company in the USA to receive a CEP for latanoprost.

Learn more about the importance of process understanding and Cayman's commercial API production