6
Oct
2026
RheaVita
About RheaVita
Certifications
Categories
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Country/Region:Belgium
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On CPHI since:2023
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Certificates:1
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Employees:1 - 24
Company types
Primary activities
Products from RheaVita (3)
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Product RheaLyo GMP-Flex Freeze-Dryers
RheaVita has turned pharmaceutical freeze-drying from a multi-day process into a fast, flexible, and agile process while guaranteeing quality at the individual product level. This is critical to delivering new therapeutics all over the world and making medicines more readily available. The GMP Continuous ... -
Product RheaLyo Mono Freeze-Dryer
The Single Vial Continuous Freeze-Drying System is specifically designed for R&D production based upon the RheaVita Continuous Freeze-Drying Technology. The equipment is perfectly suited for very fast formulation and process development and optimization using a very limited amounts of product by mimick... -
Product Services offered
1. Process development service: RheaVita has built deep knowledge to dry a broad range of biological products. We can design a spin freeze-drying recipe for your compounds in just a few days. 2. Formulation advice: RheaVita’s years of expertise and knowledge of biopharmaceutical stability and degradation a...
RheaVita Resources (11)
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News Astellas Feasibility Study for Continuous Freeze-drying
Spin-freezing is a novel technology to solve know batch freeze-drying issues. This technology enables us to reduce processing time as well as easily detect foreign matters. Also, reconstitution time is significantly reduced. Spin-freezing technology can be leveraged to continuous freeze-drying (Continuous FD) for larger production scale. Feasibility study for Continuous FD using RheaLyo™ Mono Freeze-Dryer as single vial unit (SVU) from RheaVita BV was conducted to demonstrate its benefits on the common issues seen in Batch FD.
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Brochure RheaVita at a glance
Overview products and services by RheaVita (lyophilization) -
News From Conventional Batch Lyophilizer to Continuous Spin-Freeze-Drying Technology: Lyophilized Drug Product in hours instead of days
Continuous spin freeze-drying integrates spin-freezing, primary drying, and secondary drying into a fully continuous process. During spin-freezing, vials are rotated under a controlled gas flow, creating a thin and homogeneous frozen layer along the vial wall. This configuration enhances heat and mass transfer, accelerates sublimation, and has the potential to substantially reduce freeze-drying cycle times while maintaining product quality.
In this context, the R&D Formulation and Analytical Development Laboratory of Thermo Fisher Scientific (Monza, Italy) investigated the application of the RheaVita continuous lyophilization technology to a challenging formulation, in comparison with a conventional lyophilizer.
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Brochure Astellas use case
Data from Astellas. -
Brochure Thermo Fisher use case
Data from thermo Fisher -
Video GMP-Flex freeze-dryer
Overview of the automated GMP-Flex continuous, controlled lyophilization technology by RheaVita. -
Whitepaper ADC
Advancing ADC Lyophilization: The Value of RheaVita’s RheaLyo™ Continuous Freeze-Drying Technology for Antibody–Drug Conjugates (ADCs)
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Whitepaper Time-to-Market
Faster time-to-market for lyophilized drugs and vaccines thanks to the RheaLyo™
Continuous Freeze-Drying Technology
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Brochure RheaVita overview
Summary of our products and services. -
Brochure BSL2
The Mono freeze-dryer expanded with a BSL-2 option. -
Whitepaper mRNA LNP
Stabilizing mRNA LNPs via controlled continuous freeze-drying


