Centauri Therapeutics to develop novel anti-infective therapeutics

Company has acquired Alphamer immuno-therapeutics platform technology.

The company has also appointed Dr Clive Dix as Chairman and secured the first tranche of a £3M raise to develop its first lead candidate. The funding will be used to develop its first lead Alphamers against anti-microbial resistant (AMR) pathogens, which pose an increasing threat to human health. Investors include Animatrix Capital LLP, a regional investment fund, and private investors.

Centauri Therapeutics’ decision to acquire the Alphamer platform was made following the publication of a successful preclinical proof of principle study by Professor Victor Nizet, a professor at UCSD, California and a leading academic in the field of antimicrobial immunity.

Clive Dix has more than 25 years’ experience in the life sciences industry and is one of the UK’s leading pharma and biotech entrepreneurs. Clive was formerly co-founder and Chief Executive of Convergence Pharmaceuticals Ltd., acquired by Biogen Idec in 2015 in a deal worth up to $675 million. Previously, he was a founder and CEO of PowderMed Ltd, acquired by Pfizer in 2006; and Chairman of Auralis Ltd where he managed a successful US trade sale. Before that he was a main Board Director of PowderJect Pharmaceuticals until its acquisition by Chiron in 2003.

Centauri Therapeutics has established a core R&D facility at Discovery Park in Sandwich, Kent, with an experienced team of industry scientists focused on discovery, optimisation and development of novel Alphamers targeting acute hospital acquired infections.

Mike Westby, CEO of Centauri Therapeutics, commented: “The emergence and rapid global spread of AMR pathogens means that there is a large potential market to treat life-threatening intractable diseases. Alphamers are chemically synthesised molecules designed to redirect the body’s own immune system to more effectively fight infection. As well as the new financing announced today we are also proud to announce the appointment of Clive Dix as our Chairman. Clive’s experience in successfully developing therapeutic platform technologies will be invaluable.”

Clive Dix, Chairman of Centauri Therapeutics, said: “The Alphamer platform technology is a unique opportunity to assemble well-characterised building blocks to produce novel and IP-protected medicines. Centauri Therapeutics has assembled a team of industry-experienced R&D scientists guided by a proven leadership.”