SAFC Launches ADC ExpressSM to Expedite Preclinical Antibody Drug Conjugation Services

Sigma-Aldrich Corporation has announced that SAFC Commercial, its custom manufacturing services business unit, has introduced ADC Express preclinical development services within its Contract Manufacturing Services portfolio. This ADC (antibody drug conjugate) offering includes rapid preparation of development grade conjugate constructs for clients to use in their target molecule identification.

“ADC Express reflects our drive to offer our customers a full service solution to the development of their ADCs. SAFC is the reliable, experienced partner that customers can depend on as they navigate the complex and challenging discovery phase of ADCs,” said Dr Cynthia Wooge, Global Strategic Marketing Manager for SAFC. “ADC Express allows our customers to leverage our platform expertise when they need it most, providing development grade constructs to fit timeline and budget obligations.”

The ADC Express service features access to SAFC‘s platform technology, including:

•       Prep scale: 10-200 mg ADC construct +/- column purification

•       Certificate of testing with key quality attributes

•       ADC concentration

•       Payload density DAR (drug antibody ratio)

•       Monomer/aggregate content

The delivery results are:

•       Rapid production of development grade ADC constructs

•       Key analytical characterization

•       Cost effective expert assistance for discovery