OralogiK™ - Controlled release technology

BDD has developed an erosion based controlled release technology that provides unrivaled control of drug release at a pre-defined time with no release of drug prior to the pulse. The technology is an erodible barrier layer that is wrapped around a drug containing core to give a tablet in tablet dose form. The barrier layer is designed to erode at a controlled rate until eventually the drug is released from the core tablet and the length of the delay period can be tailored between 2 and 8 hours by simply changing excipient ratios.

The barrier layer works independently of the core so can be applied to almost any drug where there is a therapeutic need, with minimal development. The release can be sustained or pulsed release giving unparalleled versatility.

 The OralogiK barrier layer can be readily film coated, allowing addition of an immediate release dose which can be the same or different to the drug in the core tablet.

These wide-ranging formulation attributes permit the realisation of complex delivery profiles in which one or more drugs can be combined into a single tablet, using proven manufacturing technologies to achieve new therapeutic objectives, previously unattainable.