Amylin(Elo)

Amylin(Elo)
Product Description

Elo is a novel highly selective long-acting amyin 1 receptor (AMYTR) agonist modified with C20 fatty diacid sidechain, with plasma half-life of 12.9-15.3 days and once-weekly subcutaneous injection. Amyin is co-secreted with insulin fromhuman pancreatic B-cells, which suppresses postprandial glucagon release, delays gastric emptying and triggers satiety signalin brain to cut calorie intake. Eloralintide preferentially binds to AMY1R with 12-fold selectivity over calcitonin receptor (CTR) and11-fold over AMY3R to reduce gastrointestinal side effects. Phase ll clinical data proved up to 20.1 % body weight reduction atweek 48, mainly fat loss instead of lean mass loss, applicable for obesity & T2DM APl development and combined medicationwith GLP-1/GIP dual agonist such as tirzepatide.

Nanjing Cellnuo Biotechnology Co.,Ltd.

  • Country/Region:
    China
  • On CPHI since:
    2023
  • Certificates:
    3
  • Employees:
    50 - 99
Company types
Biopharmaceutical company
CMO/CDMO
Manufacturer/Innovator
Primary activities
API Producer
Biopharmaceutical
Contract Manufacturer
Contract Research Organisation
Cosmetic Ingredients
Specifications
  • CAS Registry Number
    2883634-40-8
  • Details
    5g,10g,50g,100g
  • Model
    API
  • Supplied from
    China

Nanjing Cellnuo Biotechnology Co.,Ltd.

  • Country/Region:
    China
  • On CPHI since:
    2023
  • Certificates:
    3
  • Employees:
    50 - 99
Company types
Biopharmaceutical company
CMO/CDMO
Manufacturer/Innovator
Primary activities
API Producer
Biopharmaceutical
Contract Manufacturer
Contract Research Organisation
Cosmetic Ingredients

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