berberine hydrochloride

This product is an alkaloid from Rutaceae plant Phellodendron Chinese Schneid in phellodendron bark extract refined. Yellow needle crystal powder, very bitter taste. This product is a natural antibiotic, for the treatment of bacterial dysentery, typhoid fever, epidemic meningitis, tonsillitis.A kind of alkaloid. Molecular formula [C20H18NO4]+. Also called berberine. There are many plants in Berberidaceae in 4 families and 10 genera. The berberine can precipitate out yellow needle like crystals from ether. Melting point 145. Soluble in water, soluble in benzene, ether and chloroform. Berberine is a quaternary ammonium alkaloids, its salts in water solubility are relatively small, such as hydrochloride as 1: 500, sulfate was 1: 30. The crystal of Berberine from water or dilute ethanol contains 5.5 molecules of crystallization water; if it is crystallized from chloroform, acetone or benzene, it also contains the corresponding crystalline solvent molecules. The three different forms of berberine, such as quaternary ammonium type, aldehyde type and alcohol type, were obtained by using different alkali treatments. Berberine of hemolytic streptococcus, Staphylococcus aureus, Neisseria gonorrhoeae and Freund, Shigella dysenteriae were antibacterial effect, and enhancing white blood cell phagocytosis. Berberine hydrochloride (commonly known as berberine hydrochloride) has been widely used in the treatment of enteritis, bacillary dysentery, and also have certain effects on pulmonary tuberculosis, scarlet fever, acute tonsillitis and respiratory tract infection.