(-)-Blebbistatin

(-)-Blebbistatin
Product Description

(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly.

BOC Sciences

  • Country/Region:
    United States
  • On CPHI since:
    2022
  • Employees:
    250 - 499
Company types
CMO/CDMO
Contract Research Organisation (CRO)
Manufacturer/Innovator
Primary activities
API Producer
Chemical Development
Contract Manufacturer
Laboratory Services
Supply Chain
Specifications
  • CAS Registry Number
    856925-71-8
  • Details
    (-)-Blebbistatin, a cell-permeable small molecule, inhibits myosin II ATPase activity potently and specifically. The typical capacity of this molecule to inhibit non-muscle myosin II affects cell motility, cytokinesis, and other actin-myosin activities, making it widely employed in biological and biochemical research. (+)blebbistatin is the inactive enantiomer of (-)blebbistatin.

  • Selling Points
    Brand Name
  • Supplied from
    United States
  • Measured In
    milligram

BOC Sciences

  • Country/Region:
    United States
  • On CPHI since:
    2022
  • Employees:
    250 - 499
Company types
CMO/CDMO
Contract Research Organisation (CRO)
Manufacturer/Innovator
Primary activities
API Producer
Chemical Development
Contract Manufacturer
Laboratory Services
Supply Chain

More Products from BOC Sciences (2)

  • N1-MethylpseudoUridine-5'-Triphosphate

    Product N1-MethylpseudoUridine-5'-Triphosphate

    N1-MethylpseudoUridine-5'-Triphosphate is a modified NTP for incorporation into messenger RNAs (mRNA) using T7 RNA Polymerase. Incorporation of N1-methylpseudouridine can reduce the immunogenicity of the resulting mRNA. The sodium form N1-MethylpseudoUridine-5'-Triphosphate Sodium (B2706-358101) is in stoc...
  • Polyquaternium 1

    Product Polyquaternium 1

    Polyquaternium 1 is an ophthalmic preservative.

BOC Sciences resources (2)

  • News Prof. Gang Zheng to Share Insights on Theranostic Lipid Nanoparticles in Exclusive BOC Sciences Webinar

    BOC Sciences hosts Prof. Gang Zheng in a groundbreaking webinar on theranostic lipid nanoparticles for cancer medicine.
  • Industry Webinar Webinar: Engineering Microbes and Microbial Communities for Sustainable Bioproduction

    This webinar, presented by Dr. Rodrigo Ledesma Amaro, focused on moving beyond traditional single-species bioprocesses to the emerging field of engineered microbial communities. 

    Highlights of the presentation*Engineering biology accelerates strain engineering to sustainably produce fuels, chemicals, materials, pharmaceuticals and food.*A new scientific frontier explores the utilisation of synthetic microbial communities for enhanced bioproduction.*Centres like the Bezos Centre for Sustainable Protein create a knowledge hub for multidisciplinary research and convergence of science, translation, education, and policy.
    Free registration here https://www.bocsci.com/webinar-engineering-microbes-and-microbial-communities-for-sustainable-bioproduction.html