Clinical CDMO

Clinical CDMO
Product Description

- Under one single roof together with discovery and pre-clinical CRO departments, capitalizing on the previously in-house gained molecule know-how, intact project teams and existing legal agreements - Stable, proprietary IcoCell® CHO cell line development platform with competitive titers & timelines, fee-for-service, license, royalty and milestone-free, with up to 10g/L titers even at non-optimized stable clone pool stage - Experience with mAbs, bi-/multi-specifics, mAb-like proteins, Fc fusions, rec. proteins, etc. - Intermittent stable IcoCell® CHO clone pools with g/L titers - Can start late & parallel in discovery already, saving 4 months’ time in CMC section - Clone selection of stable, high-titer clonal cell lines, which are process-proven and GMP-ready - USP, DSP & analytical development, non-GMP manufacturing - Pre-formulation development, stability studies, etc. - GMP manufacturing on site with latest 50L, 200L & 1000L single-use bioreactor equipment - Strategic partnership with European linker-toxin-conjugating company for ADC’s GMP manufacturing

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Icosagen

  • Country/Region:
    Estonia
  • On CPHI since:
    2024
  • Certificates:
    2
  • Employees:
    100 - 249
Company types
Biopharmaceutical company
CMO/CDMO
Contract Research Organisation (CRO)
Contract Service
View company profile

Icosagen

  • Country/Region:
    Estonia
  • On CPHI since:
    2024
  • Certificates:
    2
  • Employees:
    100 - 249
Company types
Biopharmaceutical company
CMO/CDMO
Contract Research Organisation (CRO)
Contract Service
View company profile

More Products from Icosagen (4)

  • Pre-Clinical CRO

    Product Pre-Clinical CRO

    - Transient protein production CHO (& HEK) from proprietary QMCF expression platform - Hundreds of protein candidates in parallel - From mgs to grams, from ml’s to dozens of liters scale (chemically defined, serum-free medium) - Protein for in-vitro and in-vivo purposes - Automated, high-throughput pla...
  • Antibody DISCOVERY

    Product Antibody DISCOVERY

    - Antigen protein production in HEK & CHO - Antibody discovery in chicken, rabbits, alpaca VVH’s and by Phage Display in vitro - Functional antibody discovery against integral multi-pass transmembrane protein (such as transporters, GPCRs, & ion channels) by proprietary pseudotyped VLP-based display techn...
  • CRDMO Concept & Benefit

    Product CRDMO Concept & Benefit

    - When teaming up with Icosagen, you combine forces with a single expert team at one single site - To navigate your protein project together, from antibody discovery over transient R&D milligrams to stable IcoCell® CHO cell line development clinical GMP kilograms - One team, one site, your project - Sav...
  • Icosagen as Technology & Service Provider

    Product Icosagen as Technology & Service Provider

    - Mammalian protein drug candidate CRDMO - Uniquely combining pre-clinical CRO and clinical CDMO capabilities - 230+ people, >200 scientists (>45 PhD’s) all in one single site - Founded 1999, fully independent, successful 26-yr family-business - Integrated, modular CRDMO services, from discovery to 100...