Croscarmellose Sodium

Croscarmellose sodium occurs is an odorless, white or grayish white powder. It is used in oral pharmaceutical formulations as a disintegrant for capsules, tablets, and granules. In tablet formulations, croscarmellose sodium may be used in both direct-compression and wet-granulation processes. When used in wet granulations, the croscarmellose sodium should be added in both the wet and dry stages of the process (intra- and extragranularly) so that the wicking and swelling ability of the disintegrant is best utilized. Applications: in oral pharmaceutical formulizations as disintegrant for tablets, capsules & granules. Usage: 2.5% as tablet disintegrant using direct compression or we-granulation process.