Etoposide

  • Etoposide 1
  • Etoposide 2
  • Etoposide 3
Product Description

  • Product:    Etoposide
  • CAS No.:    33419-42-0
  • Molecular Formula:    C29H32O13
  • Molecular Weight:    588.56 g/mol
  • Specification:    Current USP/EP

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Aktin Chemicals, Inc

  • Country/Region:
    China
  • On CPHI since:
    2015
  • Certificates:
    2
  • Employees:
    100 - 249
Company types
CMO/CDMO
Manufacturer/Innovator
Primary activities
API Producer
Biopharmaceutical
Contract Research Organisation
Cosmetic Ingredients
Intermediates Manufacturer
Natural Extracts
Nutraceuticals
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Specifications
  • CAS Registry Number
    33419-42-0
  • Details
    Etoposide is an antineoplastic agent and an epipodophyllotoxin (a semisynthetic derivative of the podophyllotoxins). It inhibits DNA topoisomerase II, thereby ultimately inhibiting DNA synthesis. Etoposide is cell cycle dependent and phase specific, affecting mainly the S and G2 phases. Two different dose-dependent responses are seen. At high concentrations (10 µg/mL or more), lysis of cells entering mitosis is observed. At low concentrations (0.3 to 10 µg/mL), cells are inhibited from entering prophase. It does not interfere with microtubular assembly. The predominant macromolecular effect of etoposide appears to be the induction of DNA strand breaks by an interaction with DNA-topoisomerase II or the formation of free radicals.
  • Supplied from
    China
  • Measured In
    gram; kilogram; milligram
More specifications Fewer specifications

Aktin Chemicals, Inc

  • Country/Region:
    China
  • On CPHI since:
    2015
  • Certificates:
    2
  • Employees:
    100 - 249
Company types
CMO/CDMO
Manufacturer/Innovator
Primary activities
API Producer
Biopharmaceutical
Contract Research Organisation
Cosmetic Ingredients
Intermediates Manufacturer
Natural Extracts
Nutraceuticals
View company profile

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