Inline Particle Probe IPP 80-P

Inline Particle Probe IPP 80-P

This probe has been designed to measure the particle size distribution of powders, pellets or granules in pharmaceutical processes. The IPP-80 is used wherever the particle size has to be monitored continuously as a critical quality attribute CQA of a pharmaceutical process. It is a valuable PAT - Tool and provides valuable measurement data for use in R & D projects, in the pilot plant (for example, to reduce the number of experiments for up-scaling) and in production under GMP conditions for continuous quality monitoring and documentation - in conventional batch operation or continuous production. The probe has self-diagnostic capabilities and, together with the ParsumView software, it has all features to meet the requirements of 21 CFR 11.

Technical facts:

• Measuring range Particle Size: ........... 50– 6000 μm 
• Measuring range Particle Velocity: ..... 0.01– 50 m / s 
• Certified for ATEX Zone 0 / 20 
• Temperature range up to +100 °C at the measuring point
• Determines volume and number-based distributions with an internal class width of 1 μm 

• Continuous determination of the layer thickness and agglomerate content in pharmaceutical pellet coating in fluidized bed processes 
• Identification of individual, large particles for the detection of screen breaks 
• Determination of end point in high shear granulation 
• Monitoring fluidized bed granulation to ensure batch to batch consistency 
• Integration into PAT system for continuous fluidized bed granulation 
• Measurement of the grain size in roller mills for setting the grinding gap 
• Monitoring the particle size for controlling the layer height during fluidized bed drying 
• Measurement of the particle size under a 3-deck screening machine to control the amount of feed
• Detection of segregation at silo discharge