REPEA® – Palmitoylethanolamide (PEA)

Palmitoylethanolamide (PEA) is a natural product, present in several types of food (eggs, soy oil, peanuts etc.) and is naturally produced by our body. Its physiological role was studied and firstly described in 1992 by the Nobel Prize Rita Levi Montalcini. PEA act at peripheral level by inhibiting the mastocytes’s degranulation. Mastocytes are recruited at the site of inflammation and via degranulation release pro-inflammatory cytokines such as TNF alpha, IL2. A large number of clinical studies are supporting its use in chronic peripheral pain management, neuroinflammation, premenstrual syndrome, osteoarthritis conditions.

Frau Pharma, as a leading Palmitoylethanolamide manufacturer & Palmitoylethanolamide supplier, produces REPEA®, a premium product developed in GMP-certified pharmaceutical-grade facility in Italy. Manufactured in our Italian factory Palmitoylethanolamide plant, REPEA® meets strict pharmaceutical and nutraceutical quality standards.