Tacrolimus

1. Purpose   - Immunosuppressant  

2. Effects/Benefits   -  Primarily used to reduce the risk of organ rejection in patients with allogeneic organ transplantation. It is also used to treat autoimmune diseases, such as atopic dermatitis.  


3. Main functions   -  Tacrolimus is a polyketide macrolide lactone with immunosuppressive activity.  


4. Primary advantages   - Tacrolimus is a highly potent immunosuppressant. Compared to a similar immunosuppressant cyclosporine, tacrolimus has been shown to be 10 to 100 times more potent and have less side effects, such as hypertension, hirsutism and gingivalhyperplasia.