Tezacaftor
Product Description
Solarte
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Country/Region:China
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On CPHI since:2026
Categories
Specifications
Solarte
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Country/Region:China
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On CPHI since:2026
More Products from Solarte (4)
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Product Deutivacaftor
Deutivacaftor, also known as ivacaftor-d9, VX-561, or CTP-656, is a precision-deuterated analog of ivacaftor in which nine hydrogen atoms are replaced by deuterium. It is a CFTR potentiator that increases the probability of channel opening of CFTR proteins delivered to the cell surface. Deuteration slows d... -
Product Elexacaftor
Elexacaftor is a CFTR corrector that binds to the F508del-CFTR protein and stabilizes its conformation, thereby facilitating its processing and trafficking to the cell surface. When combined with tezacaftor and ivacaftor, elexacaftor and tezacaftor bind to different sites on the CFTR protein and have an ad... -
Product Ivacaftor
Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. It binds directly to the CFTR protein at the cell surface and increases the open probability of the ion channel, thereby enhancing chloride transport across cell membranes. It is indicated for the treatment of cystic fib... -
Product Vanzacaftor
Vanzacaftor (VX-121) is a CFTR corrector for class II CFTR mutations, the most common being F508del. It improves the processing and trafficking of defective CFTR proteins, allowing them to reach the cell surface and function properly. Vanzacaftor is administered as part of a triple combination with tezacaf...