Shandong Topscience Biotech Co., Ltd.

  • Sodium Hyaluronate Injection Grade
  • Sodium Hyaluronate Eye-drop Grade
  • Sodium Hyaluronate Cosmetics Grade
  • Sodium Hyaluronate Food Grade
About Shandong Topscience Biotech Co., Ltd.

Shandong Topscience Biotech Co., Ltd. established in 2005, it is a state-level high-tech company, specialized in R&D, production, sales of biochemical APIs, cosmetic and food ingredients. The company's products include Sodium Hyaluronate(SH), Alpha-Arbutin, Ascorbyl Glucoside, Sulglycotide, etc. The quality could be guaranteed by the effective management from starting materials to product release.
Topscience is one of the few manufacturers of Sodium Hyaluronate with GMP certification in China and the status of API registration number is A. Sodium Hyaluronate API includes Injection grade, Eye-Drop grade and Excipients grade. The molecular weight of the Sodium Hyaluronate covers all the ranges of large, medium and small, which can meet various medical uses. The products are produced by microbial fermentation, and the raw materials used are non animal sources. They have the advantages of ultra-low impurity level, ultra-low endotoxin level, ultra-low metal impurity residue and ultra-low microbial pollution.

We are working on lower levels of bacterial endotoxins, and the result of bacterial endotoxins in Injection Grade Sodium Hyaluronate is 0.001 IU/mg. The bacterial endotoxins in Sodium Hyaluronate are less than 0.05 IU/mg in the pharmaceutical Industries at present according to the pharmaceutical specification. While the result of Topscience is not more than 0.001 IU/mg, which is 1/50 of the Ph. Eur. Specification.


Certifications
  • CN
  • 2015
    On CPhI since
  • 3
    Certificates
  • 100 - 249
    Employees
Manufacturer/Innovator
Contact info

Products from Shandong Topscience Biotech Co., Ltd.

  • Sodium hyaluronate Excipients Grade

    Product Sodium hyaluronate Excipients Grade

    Sodium Hyaluronate Excipients Grade has the registration of pharmaceutical excipients and the quality is high stability. It has the advantages of ultra-low impurity level, ultra-low endotoxin level, ultra-low metal impurity residue and ultra-low microbial pollution.

    • Microbial Fermentation product. Origin of non-animal.
    • Full range of Customized Molecular Weight.
    Application:
    ž   Intra-articular injection
    ž   Ophthalmic viscosurgical devices(OVD)
    ž   Eye drop
    ž   Dermal filler
    ž   Contact Lens Solution
    ž   Medical Lubricant
    ž   Mucosa Healing
    ž   Anti-adhesive agent
    Regulation:
    ž   GMP Compliance
    ž   Certificate of Suitability (CEP)
    ž   EU Written Confirmation Letter
    ž   Registration number in N.M.P.A. : Y20170000992 Status: A
    ž   ISO 9001 and 14001

  • Sodium Hyaluronate Eye drop Grade

    Product Sodium Hyaluronate Eye drop Grade

    Sodium Hyaluronate Eye-drop Grade has GMP certification in China and the status of API registration number is A. It has the advantages of ultra-low impurity level, ultra-low endotoxin level, ultra-low metal impurity residue and ultra-low microbial pollution.
    • Microbial Fermentation product. Origin of non-animal. 
    •  Full range of Customized Molecular Weight. 
      Application      Eye drop
         Contact Lens Solution
         Medical Lubricant
         Mucosa Healing
         Anti-adhesive agent

    Regulation:
    ž   GMP Compliance
    ž   Certificate of Suitability (CEP)
    ž   EU Written Confirmation Letter
    ž   Registration number in N.M.P.A. : Y20170000992 Status: A
    ž   ISO 9001 and 14001

  • Sodium Hyaluronate Injection Grade

    Product Sodium Hyaluronate Injection Grade

    Sodium Hyaluronate Injection Grade has GMP certification in China and the status of API registration number is A. The nucleic acid level is 0.01 (A260nm) and bacterial endotoxins is 0.001 IU/mg, which are 1/50 of the value specified in the standard of Ph.Eur. And the content of protein is lower than the detection limit (0.03%), which is in the leading position in the industry.

    •   Microbial Fermentation product. Origin of non-animal. 
    • Full range of Customized Molecular Weight. 
    Application
         Intra-articular injection
         Ophthalmic viscosurgical devices(OVD)
         Dermal filler

    Regulation:
    ž   GMP Compliance
    ž   Certificate of Suitability (CEP)
    ž   EU Written Confirmation Letter
    ž   Registration number in N.M.P.A. : Y20170000992 Status: A
    ž   ISO 9001 and 14001

  • Alpha-arbutin

    Product Alpha-arbutin

    Shandong Topscience Biotech Co., Ltd. is the leading manufacturer of Alpha-arbutin.
    • one of the most effective andsafe lightening ingredients in foreign countries and themost competitive lightening spot removal active substancein 21st century.
    • The stability and durability of alpha-Arbutin is 15 times more than beta-Arbutin.
    • hydroquinone is never generated.
    • No side effects of cytotoxicity, irritation and anaphylaxis.
  • Sodium Hyaluronate cosmetic Grade

    Product Sodium Hyaluronate cosmetic Grade

    Sodium hyaluronate of high molecular weight could form a breathable film at the surface of skin to moisturize the skin, protect the skin from the bacteria , dusts and UV rays. While sodium hyaluronate of small molecular weight could permeate the derma, increase the blood circulation, improve the intermediate metabolism, promote the alimentation of skin, increase the elasticity of the skin and delay the senility of skin. Furthermore, sodium hyaluonrate could promote multiplication and dissociation of epidermal cells, eliminate the oxygen free radicals and prevent and help repair the skin damage.
  • Sodium Hyaluronate Food Grade

    Product Sodium Hyaluronate Food Grade

    Sodium Hyaluronate Food Grade is produced by Microbial Fermentation and can promoting health of facial skin, antioxidation, increasing bone mineral density, improving joint function and gastrointestinal function and protecting gastric mucosa.

    Mainly in Beverage, jelly, milk products,capsules and oralliquids, together with otheringredients as food supplement.
    Oral intake could replenish the inadequate status in human body. By digestion and absorption, sodium hyaluronate could make your skin moisturizing, soft and elastic, delay aging and prevent arthritis, arteriosclerosis, pulse disorder, encephalanalosis and so on. Oral intake of sodium hyaluronate makes people energetic and youthful. In many developed countries such as USA, EU and Japan, it's widely applied in functional food.

  • Sodium Hyaluronate Medical Device Grade

    Product Sodium Hyaluronate Medical Device Grade

    Sodium Hyaluronate Medical Device Grade
    Sodium Hyaluronate Medical Device Grade is a kind of Molecular Weight Sodium Hyaluronate Topical Grade 1.2 ~ 3.6 m3/kg. It suitable for medical device of external application. And not suitable for parenteral administration, dermal fillers and not to be used as an API.

  • Sodium Hyaluronate Medical Injection Grade

    Product Sodium Hyaluronate Medical Injection Grade

    Sodium Hyaluronate Medical Injection Grade
    Sodium Hyaluronate Medical Injection Grade  is a kind of Molecular Weight Sodium Hyaluronate Topical Grade 1.2 ~ 3.2 m3/kg. It Suitable for medical device of parenteral administration and dermal fillers. And not to be used as an API.
  • Sodium Hyaluronate Topical Grade

    Product Sodium Hyaluronate Topical Grade

    Sodium Hyaluronate Topical Grade
    Sodium Hyaluronate Topical Grade is a kind of Molecular Weight Sodium Hyaluronate Topical Grade 0.047 ~ 3.6 m3/kg. It suitable for medical device of external application. And not suitable for parenteral administration, dermal fillers and not to be used as an API.

Shandong Topscience Biotech Co., Ltd. Resources

  • News SODIUM HYALURONATE PHARMA GRADE

    · GMP Certificate and Excellent Quality guaranteed by CoS, KDMF, Form 41, ISO, Halal, Kosher, etc.

    · Highly Purified Sodium Hyaluronate with an extreme control of Bacterial Endotoxins, which is lower than 0.001 lU/mg.