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3M Deutschland GmbH
About 3M Deutschland GmbH
3M Separation and Purification Sciences Division provides unique bioprocessing solutions for clarification and purification in the recombinant protein market segment. To boost your bioprocessing efficiency, we offer a robust portfolio of products – from membranes and depth filters to hybrid chromatographic purifiers.
Indeed, 3M™ LifeASSURE™ Filter, 3M™ Zeta Plus™ Depth Filter and 3M™ Emphaze™ AEX Hybrid Purifier provide robust purification platformability across diverse biopharmaceutical modalities. Removal of HCP, DNA and endotoxins during clarification enables higher yield, elimination or reduction in size of unit operations, and ultimately overall process economics improvements.
For more information on our portfolio, please visit us on our website: https://www.3mdeutschland.de/3M/de_DE/biopharmazie/.
Products from 3M Deutschland GmbH
The 3M™ Emphaze™ AEX Hybrid Purifier is a synthetic, multi-mechanism single-use purifier used for biopharmaceutical clarification. It delivers consistent, high purity clarified process fluid by removing soluble and insoluble impurities, such as DNA, HCP, and celldebris, through a combination of chromatographic and size exclusion mechanisms.
Customers experience benefits in typical monoclonal antibody purification processes:
• Nominal 30% HCP and greater than 4 log DNA reduction.
• Consistent output turbidity (<5 NTU).
• Increase product purity post-protein A.
• Downsizing of the sterilizing grade membrane.
• Reduce turbidity post viral inactivation/neutralization step.
• Reduce impurities load on downstream AEX column.
3M’s range of LifeASSURE™ Membrane filters feature unique Advanced Pleat Technology that maximises the useful surface area of the filter while maintaining open flow paths between media pleats. Our membrane filters are optimised for applications requiring critical sterilisation where 0.2μm absolute-rated filtration is required.
For optimal clarification of biopharmaceutical manufacturing fluids, 3M’s extensive line of depth filters is versatile and adaptable for many processes. Our pharmaceutical-grade filters have high contaminant-holding capacity and provide economical filtration with reliable particle reduction.
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