Gattefossé SAS

Labrafac™ MC60 (glycerol monocaprylocaprate) is a water-insoluble surfactant used in oral lipid-based formulation for bioavailability enhancement of poorly water-soluble, and poorly permeable drugs. It acts as a solubilizer and as an intestinal permeation enhancer.

Emulfree® Duo is a ready-to-use system. It has been designed to stabilize the oil phase within a bi-gel, an emerging topical formulation, by ensuring fine and homogeneous dispersion in the aqueous phase. As a PEG-free excipient, it is ideal for sensitive skins and mucosea.

Gelucire® 59/14 is a mixture of lauroyl PEG-32 glycerides and PEG 6000 and has surfactant properties. It is a self-emulsifying excipient used for oral bioavailability enhancement of poorly water-soluble drugs, thanks to its high solubilizing capacity.

Capryol 90 (propylene glycol monocaprylate) is a nonionic water-insoluble surfactant used as cosurfactant in oral lipid-based formulation SEDDS and SMEDDS. Cosurfactant and solubilizer in topical dosage forms.

Maisine® CC (glyceryl monolinoleate) is an oil composed of long-chain mono-, di-, and triglycerides for lipid-based formulations to solubilize and increase oral bioavailability of poorly water-soluble lipophilic APIs. Used in self-emulsifying lipid formulations (SEDDS and SMEDDS) as an oily vehicle. Its hi...

Providing high-quality functional excipients

Our lipid excipients are manufactured using vegetable oils (including corn, apricot kernel or coconut oil), a wide array of plant-derived fatty acids, and alcohols such as polyglycerol, fatty alcohols, polyethylene glycol and propylene glycol.

Depending on the raw materials used, the esterification reaction leads to solid, semi-solid, or liquid excipients. The fatty acid chain length, the composition in terms of mono-, di- and triglycerides and alcohol-esters impact the end-product physico-chemical and functional properties.

 
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