Gattefosse S.A.

Labrafac™ MC60 (glycerol monocaprylocaprate) is a water-insoluble surfactant used in oral lipid-based formulation for bioavailability enhancement of poorly water-soluble, and poorly permeable drugs. It acts as a solubilizer and as an intestinal permeation enhancer.

Emulfree® Duo is a ready-to-use system. It has been designed to stabilize the oil phase within a bi-gel, an emerging topical formulation, by ensuring fine and homogeneous dispersion in the aqueous phase. As a PEG-free excipient, it is ideal for sensitive skins and mucosea.

Gelucire® 59/14 is a mixture of lauroyl PEG-32 glycerides and PEG 6000 and has surfactant properties. It is a self-emulsifying excipient used for oral bioavailability enhancement of poorly water-soluble drugs, thanks to its high solubilizing capacity.

Capryol 90 (propylene glycol monocaprylate) is a nonionic water-insoluble surfactant used as cosurfactant in oral lipid-based formulation SEDDS and SMEDDS. Cosurfactant and solubilizer in topical dosage forms.

Maisine® CC (glyceryl monolinoleate) is an oil composed of long-chain mono-, di-, and triglycerides for lipid-based formulations to solubilize and increase oral bioavailability of poorly water-soluble lipophilic APIs. Used in self-emulsifying lipid formulations (SEDDS and SMEDDS) as an oily vehicle. Its hi...

Compritol® 888 ATO (glyceryl dibehenate) is a glyceride with a high melting point used as a modified release agent or lubricant in tablets. Can also be used in lipid coating technologies and as lipid carrier for nanoparticles.

Compritol® 888 Pellets (glyceryl dibehenate) is a glyceride with a high melting point used as consistency agent in topical formulations.

Compritol® E ATO (for nutraceuticals) is a high melting point lipid obtained by the esterification of glycerin with C22 fatty acid, conforming to food additive status. The powder form is used as a modified release agent or lubricant for high-dose nutraceutical tablets.
PALM OIL FREE version a...

Compritol® HD5 ATO (behenoyl polyoxyl-8 glycérides) is a glyceride with an intermediate melting point containing PEG-8 esters. A powder wetting agent and lubricant for effervescent and fast-dissolving tablets.

Emulcire 61WL 2659 is a non-ionic oil-in-water emulsifier for use in association with Gelot 64 as a co-emulsifier to improve heat stability in creams. It is available in semi solid pellets form.

Geleol™ Mono and Diglycerides NF is a glyceride with an intermediate melting point used as a lipidic vehicle and modified release agent.

Geloil SC is a mixture of refined soybean oil USP-NF, glyceryl distearate USP-NF and polyglyceryl-3 dioleate USP-NF. A thixotropic suspension vehicle for nutraceutical and pharmaceutical APIs. Ready-to-use in a cold process for thermosensitive actives in soft gel capsule.

Discover Gelucire® 59/14, an add-on in Gattefossé Gelucire® range, for oral bioavailability enhancement

Providing high-quality functional excipients

Our lipid excipients are manufactured using vegetable oils (including corn, apricot kernel or coconut oil), a wide array of plant-derived fatty acids, and alcohols such as polyglycerol, fatty alcohols, polyethylene glycol and propylene glycol.

Depending on the raw materials used, the esterification reaction leads to solid, semi-solid, or liquid excipients. The fatty acid chain length, the composition in terms of mono-, di- and triglycerides and alcohol-esters impact the end-product physico-chemical and functional properties.

 
Find out quickly the excipient you are looking for! This updated version has been enriched with the precedence of use of our excipients.

Discover Labrafac™ MC60, glycerol monocaprylocaprate, an oral bioavailability enhancer.

The four Technical Centers of Excellence of Gattefossé, based in France, the United States, China and India, help our customers worldwide in their formulation projects, from concept to commercialization. Their core missions are to provide technical support, troubleshoot and share their scientific knowledge on the use of lipid-based excipients.

Discover our brand new excipient Emulfree® Duo, a ready-to-use stabilizing agent, enabler of bi-gel, an emerging topical dosage form.