Pharmaron

Pharmaron’s integrated analytical teams offer comprehensive and high-quality analytical solutions in new drug development from preclinical to commercial production. Our integrated analytical teams utilize state-of-the-art equipment to deliver advanced solutions to API and drug products to meet all analytic...

By leveraging Pharmaron’s world-class chemistry expertise at our US, UK, and China GMP facilities, our teams provide complete small molecule API development and manufacturing services for Phase I/II/III clinical development and commercial supply needs.

Pharmaron’s multi-purpose kilo labs, pilot ...

Scaling your drug program from discovery to development is challenging. By bridging our discovery and process R&D capabilities, our dedicated discovery process chemistry team enables the rapid development of candidate compounds to accelerate programs to key preclinical milestones.

Pharmaron’...

Pharmaron’s drug product development team provides complete development expertise to accommodate product and batch size needs for standalone and integrated projects. By leveraging our unique Pharmaron network in China and the UK, we support the custom manufacturing of high-quality drug products across all ...

The use of continuous flow chemistry for large-scale processing of pharmaceutical materials is accelerating. Continuous flow manufacture, often referred to as ‘flow chemistry’ or ‘continuous flow’, is a means of undertaking a chemical reaction using a continuous stream of different reagents confined in a p...

At Pharmaron, we understand that each API has its own physicochemical characteristics and formulation challenges. Based on our partners’ target product profile, our team is able to help select the most appropriate formulation design for drug products. We have experience in developing a variety of dosage fo...

Determining the most suitable lead solid form of APIs is a critical step in pharmaceutical development. The physical form impacts the physicochemical properties and influences a range of important aspects of drug development, including developability of a drug candidate, stability, bioavailability and manu...

During API chemical development, there are three words that every partner is focused on: quality, speed, and cost. Although chemical reactions may work perfectly on lab scale, moving from milligrams to kilograms or tons is not a simple, linear process. Working as an extension of your team, Pharmaron’s proc...

This webinar explores market demand and trends for small molecule drug substance late phase manufacture and supply.

Speakers include noted CMC consultant James Bruno who gives a brief overview of market dynamics and what the key needs of clients are who are transitioning into late phase and commercial small molecule drug substance production.

Dr Paul Quigley (Director Process Chemistry and Manufacture, Pharmaron) gives an overview of what is critical in terms of scale-up considerations (process scale-up fit for phase, process analytical technology, process safety, economy, velocity, materials science and technology selection).

Finally, Chris Harley (Associate Director of Manufacturing, Pharmaron) discusses manufacturing criteria (process optimisation, green metrics, technical transfer, modelling for scale, equipment selection) for successfully transitioning to commercial manufacturing.

Jet milling is a micronisation technique commonly implemented to deliver pharmaceutical API with a particle size below 10 micron with a narrow particle size distribution, thus enabling advanced product formulations.

This webinar will present a fundamental understanding of this key unit operation, cautionary tales from system setup, and will explore deeper into the current state of predictive modelling.

Speakers include experts Thoralf Hartwig (Principal Process Engineer, Pharmaron) and Filip Horvath-Gerber (Senior Process Engineer, Pharmaron). They will discuss learnings and outcomes from robust process development of jet milling within a pharmaceutical setting.