ADM SIO

About ADM SIO

ADM has an extensive range of plant based ingredients to meet your pharmaceutical needs, all manufactured under strict quality and regulatory conditions to ensure compliance. Our products can be used in a wide range of pharmaceutical applications.


PharmaEdge Ingredients (API’s and Parenteral Excipients)

The PharmaEdge products are manufactured under cGMP standards and are supported with Certificates of Suitability to the European Pharmacopoeia (CEPs) and/or FDA Drug Master Files (DMFs).

  • Refined Olive Oil IV
  • Refined Sesame Oil IV-1
  • Refined Soybean Oil IV
  • Vitamin E


PharmaPlus Ingredients (Oral & Topical Excipients)

The PharmaPlus products are compliant with the specifications of the EP and USP monographs.

  • Fully & Partially Hydrogenated Soybean Oils (VGB 4S & shortening 36)
  • Refined Pharma Oils (Soybean, Sesame, Sunflower, Rapeseed and Olive)
  • Carbohydrates :
  • Dextrose/ Glucose Monohydrate
  • Fructose
  • Maize / Corn Starch
  • Wheat Starch
  • Sorbitol Liquid (70%)
  • Maltitol Liquid
  • Lecithin’s :
  • Soy lecithin, fluid or de-oiled (powder)
  • Canola/Rapeseed Lecithin
  • Sunflower Lecithin
  • Capsulec Series – (high choline content)
  • Glycerol & Propylene Glycol
  • Bioethanol (high purity)
  • Citric Acid Anhydrous Powder USP FCC


With ADM providing the best solutions and practices for the sourcing of starting materials used to produce pharmaceutical ingredients, we aim at delivering the very best solutions to fit the requirements of the pharmaceutical industry.

ADM SIO

  • FR
  • 2015
    On CPhI since
Meet us at

CPhI Worldwide 2021

Fiera Milano, Milan, Italy
9-11 November 2021

Products from ADM SIO

  • Purified Pharmaceutical Oils (API)

    Product Purified Pharmaceutical Oils (API)

    These purified pharmaceutical oils (pharmaceutical soybean oil and pharmaceutical olive oil) are used as API for the manufacture of nutritional lipid emulsions products in parenteral nutrition. They provide a source of calories and essential fatty acids for patients who are not able to feed themselves. You will find below our list of products:
    • Pharmaceutical Soybean Oil
    • Pharmaceutical Olive Oil
    Both pharmaceutical vegetable oils fully comply with general requirements of European and US Pharmacopeia. CEP is available for products.
  • Purified Pharmaceutical Oils (Excipients)

    Product Purified Pharmaceutical Oils (Excipients)

    These highly purified oils (pharmaceutical soybean oil, pharmaceutical olive oil and pharmaceutical sesame oil) can be used as excipients in both human health (propofol, hormones, vitamins) and animal health applications (veterinary uses). They are useful in the formulations of soft gels capsules, as solubilizer for API’s insoluble in water (Cyclosporin, Dronabinol, Cannabidiol, etc.) and as texturizers. They can also be used in various syrups and lotions. ADM-SIO highly purified oils meet all the regulations in the pharmaceutical industry and are manufactured under cGMP standards. You will find below our list of products:
    • Pharmaceutical soybean oil
    • Pharmaceutical olive oil
    • Pharmaceutical sesame oil
    • VGB 4S (hydrogenated vegetable oil)
  • Carbohydrates (Excipients)

    Product Carbohydrates (Excipients)

    DEXTROSE / GLUCOSE :
    This product is a dextrose monohydrate, produced by enzymatic hydrolysis of starch, followed by purification, concentration, crystallization and drying. It is a white calibrated powder with a refreshing sweet taste and bland odour. This product meets the requirements of Ph. Eur., USP, Food Chemical Codex and Codex Alimentarius for Dextrose.

     
    FRUCTOSE:
    This product is crystalline fructose. It is produced from non-GMO cereal raw material, by enzymatic hydrolysis of starch, followed by purification, concentration, crystallization and drying. It is a white powder with a clean sweet taste and bland odour. This product meets the requirements of Ph. Eur., USP, Food Chemical Codex and Codex Alimentarius for Fructose


    NATIVE CORN / MAIZE STARCH:
    This product is a native maize food starch. It appears as a white fine powder with neutral odour and taste. This product meets the requirements of Ph. Eur., USP, Food Chemical Codex and Codex Alimentarius for Native Corn/Maize Starch.


    NATIVE WHEAT STARCH:
    This product is extracted from selected species of French wheat. It is a binding, thickening and bulking agent, suitable for various food products. This product meets the requirements of Ph. Eur., USP, Food Chemical Codex and Codex Alimentarius for Native Wheat Starch.

ADM SIO Resources

  • Brochure Refined Olive Oil

    Refined Olive Oil is a pharmaceutical oil, suitable for use as API or excipient in human and veterinary applications in injectable, oral or topical dosage forms. It is obtained by refining of virgin olive oil, obtained by cold expression from the ripe fruit of Olea Europaea Linné, Refined Olive Oil fully complies with the European Pharmacopoeia monograph “Olive oil, refined”<1456> and USP-NF monograph “Olive Oil” including general chapters and is intended for use in the manufacture of parenteral preparations. Refined Olive Oil IV is manufactured under cGMP according to the ICH Q7 Good Manufacturing Practice (GMP) Guidance for APIs and regulatory supported with a certificate of suitability (CEP, No. R0-CEP 2015-167) and US DMF (type IV, # 034 152 & type II, # 035 559).

    HIGH STABILITY GUARANTEE

    Stability studies performed according to the International Conference on Harmonization (ICH) Q1A Quality Guideline show that Refined Olive Oil IV is perfectly stable over a 36-month shelf life period.


    PACKAGING

    ADM-SIO’s Refined Olive Oil IV is available in 56,5 Kg or 200 Kg tight-head metal drums that are filled under nitrogen in an ISO 8-classified cleanroom.
  • Brochure Refined Soybean Oil

    Refined Soybean Oil is a pharmaceutical oil, suitable for use as API or excipient in human and veterinary applications in injectable, oral or topical dosage forms. It is obtained from seeds of Glycine max (L). Merr. (Glycine hispida (Moench) Maxim.) by extraction of crude soybean oil followed by a refining process. Refined Soybean Oil IV fully complies with the European Pharmacopoeia monograph “Soya-bean oil, refined”<1473> and USP-NF monograph “Soybean Oil” including general chapters and is intended for use in the manufacture of parenteral preparations. Refined Soybean Oil IV is manufactured under cGMP according to the ICH Q7 Good Manufacturing Practice (GMP) Guidance for APIs and is regulatory supported with a certificate of suitability (CEP, No. R1-CEP 2011-115) and US DMF (type IV, # 028 528 & type II, # 035 560).


    HIGH STABILITY GUARANTEE

    Stability studies performed according to the International Conference on Harmonization (ICH) Q1A Quality Guideline show that Refined Soybean Oil IV is perfectly stable over a 36-month shelf life period.


    PACKAGING

    ADM-SIO’s Refined Soybean Oil IV is available in 56,5 Kg or 200 Kg tight-head metal drums that are filled under nitrogen in an ISO 8-classified cleanroom.
  • Brochure Refined Sesame Oil IV-1

    Refined Sesame Oil IV-1 is obtained from the seeds of one or more varieties of Sesamun indicum L. (Fam. Pedaliaceae) by expression followed by a refining process. Refined Sesame Oil IV-1 complies with the specifications of European Pharmacopoeia monograph “Sesame Oil, refined” <0433> and NF/US Pharmacopeia monograph “Sesame Oil”, intended for use in the manufacture of parenteral preparations. Strict selection, based on starting materials and product analysis, allows deliveries of homogen batches, in accordance with the Pharmaceutical GMP requirements. Supported with Drug Master File (DMF type IV, # 031 697) for excipients submitted to the U.S. Food and Drug Administration (FDA).


    HIGH STABILITY GUARANTEE

    Stability studies performed according to the International Conference on Harmonization (ICH) Q1A Quality Guideline show that Refined Sesame Oil IV-1 is perfectly stable over a 36-month shelf life period.


    PACKAGING

    ADM-SIO’s Refined Sesame Oil IV-1 is available in 56,5 Kg or 200 Kg tight-head metal drums that are filled under nitrogen in an ISO 8-classified cleanroom.

  • Brochure Fully Hydrogenated Soybean Oil VGB 4S

    Our VGB 4S is a high melting point fully hydrogenated soybean oil presented in flakes.

    It complies with the specifications of:European Pharmacopoeia “Soybean Oil,  hydrogenated” <1265> monographUSP/NF Pharmacopeia “Hydrogenated  Soybean Oil” monograph
  • Whitepaper Refined Sesame Oil IV-1

    Sesame seeds (Sesamum indicum L.) have been grown in tropical regions throughout the world since prehistoric times. It has been one of the fi rst crops processed for oil production.

    Sesame oil has been used for healing wounds for thousands of years and is mentioned in the Vedas in India as is mentioned in the Vedas in India as ideally suited for the human species.

    Nowadays it is used in food, nutraceutical, cosmetic and pharmaceutical industries.
  • Whitepaper Managing the natural variability of plant-based pharmaceutical ingredients

    Pharmaceutical ingredients play a key role in drug formulation. Variations in their composition and physicochemical properties can have significant impact on the final drug product performances like safety, physical and chemical stability and bioavailability. In the recent past, ingredient variability has been at the origin of FDA recalls.
  • Whitepaper Use of high melting point solid vegetable oils in encapsulation processes

    Encapsulation relates to technologies that enable the incorporation of a compound into individualized small particles. Depending on the process applied, these particles can have different sizes, shapes and specific structures. Many kinds of active compounds can be encapsulated with many different encapsulation materials. High melting point solid vegetable oils are one of them.