Aphthron

Aphthron
Product Description

Mucoadhesive tablets for treatment of Aphthous Stomatitis
Recurrent Aphthous Stomatitis (RAS) is among the most common painful oral conditions, with up to 66% of the world’s population affected. These wounds are often called canker sore.
Aphthous Stomatitis causes small, painful benign ulcers inside the mouth that may appear on the tongue and on the inside linings of the cheeks, lips, and throat. Wounds usually appear as white, grey, or yellow in color, with a red border. Aphthous ulcers typically last for 10 painful days and they heal spontaneously normally without leaving a scar.
There are a number of possible triggers to RAS, each of which is capable of producing the disease in different subgroup. In most cases, the cause is unclear, but is thought to be multifactorial. It is suggested that RAS is not a single entity but rather a group of conditions with different causes. It has been associated with other autoimmune diseases.
There is no certain cure for RAS, but it is known to be not contagious and that topical treatment can be used to assist in the healing process.
Aphthron is a mucoadhesive tablet which adheres to the ulcer thus creating a mechanical barrier that protects the ulcer from contact with the tongue, teeth, food, and pH changes in the mouth.
Aphthron contains Hyaluronic Acid 0.5% which protects the ulcer, enhances tissue hydration and significantly shortens the healing process by isolating the wound from irritants.
Aphthron also contains Menthol as a cooling ingredient; it induces a local numbing sensation by extracting heat form the tissue it is applied on. This cooling sensation causes local desensitization of sensory nerves, leading to a decrease in pain transmission to the central nervous system.
Aphthron acts via a special mucoadhesive, slow release mechanism. The tablet sticks to the soft tissue in the mouth, on top of the wound in a way that ensures the release of the active ingredient into the ulcer for a prolonged period of time until the tablet is completely dissolved and disintegrated (up to 4 hours).
This mechanism provides a long lasting and highly effective pain relief to the treated ulcer.

 

Tree of Life Pharma Ltd

  • IL
  • 2015
    On CPHI since

Tree of Life Pharma Ltd

  • IL
  • 2015
    On CPHI since

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