Sterigenics U.S., LLC

There is much to consider when choosing a sterilization technology. Sterigenics’ expert advisors look forward to working with you to understand and achieve your unique product goals. We offer all major sterilization technologies: Gamma Irradiation, Ethylene Oxide & Electron Beam as well as innovativ...

There is much to consider when choosing a sterilization technology. Sterigenics’ expert advisors look forward to working with you to understand and achieve your unique product goals. We offer all major sterilization technologies: Gamma Irradiation, Ethylene Oxide & Electron Beam as well as innovativ...

There is much to consider when choosing a sterilization technology. Sterigenics’ expert advisors look forward to working with you to understand and achieve your unique product goals. We offer all major sterilization technologies: Gamma Irradiation, Ethylene Oxide & Electron Beam as well as innovativ...

Development of a holistic path to validation of bulk sterilized pharmaceuticals, from determination of the maximum dose through sterilization dose establishment and process qualification. This presentation provides guidance to optimize doses, testing strategies, and necessary considerations for a successful routine sterilization program.

Eric Offermann and Bernd Zeiss will speak about Nitrogen Dioxide (NO2) as a new sterilization method and an alternative to EtO gas. A joint study carried out by Gerresheimer, Sterigenics and Früh, showed that NO2 is well suited to terminally sterilize prefilled ophthalmic syringes. The following 5 topics will be addressed in detail: Comparison of EtO vs. NO2 penetration into the filled syringe. Analyze gas ingress through 4 different plunger stoppers including silicone oil-free and standard rubber plungers. Scrutinize gas ingress through 2 different cap designs based on different elastomer properties. Investigate gas permeation through COP plastic barrels compared to glass. Check if the final blister has an influence on either sterilization method. The ultimate objective of this study was to offer the best syringe design and packaging paired with the most suitable sterilization modality to pharma customers.

Packaging is an integral part of the design for pharmaceutical products and medical devices. Not only does one need to take into account the look, feel, and protective qualities of the packaging but design must be considered when determining the sterilization technology. Determining the sterilization technology early in the design process, and concurrently working with your sterilization supplier can minimize risk and optimize outcomes. This presentation will cover packaging basics including materials, methods of sterilization (Ethylene Oxide and Radiation) and also explore packaging design challenges and solutions for Ethylene Oxide process validation

In this webinar, originally part of Pharmapack Europe 2022, S. Ross Tsakas, Pharmaceutical Segment Leader, Sterigenics discusses parenteral drug development. Parenteral drugs and the drug development lifecycle represent complexities across the multi-year, multi-million pledges made. With over 90 years of experience supporting the pharmaceutical, biotech, and medical device industries, we have identified 5 key hurdles: sterility, quality control, compliance, regulatory affairs, and routine manufacturing, we will delve into each challenge in a systematic, concise, yet compelling manner. As sterilization becomes a top-of-mind priority for clients along the entire supply chain, we stand poised to facilitate bolstering global health through strategic support initiatives that expedite products to market and help ensure their safety.