Covance Expands Drug Metabolism Services
Covance announces the expansion of its market-leading drug metabolism services to include drug-transporter interactions with eight human transporters.
Covance Inc., one of the world’s largest and most comprehensive drug development services companies, announced Wednesday it has expanded its drug metabolism services to include drug-transporter interactions with eight human transporters.
The New Jersey-based company now offers assessment of drug-transporter interactions involving major human transporters key to drug disposition in a stably transfected, cell-based format.
The eight cell lines in the drug-transporter interactions service include P-glycoprotein (P-gp/MDR1), breast cancer resistant protein (BCRP), organic cation transporters 1& 2 (OCT1 & OCT2), organic anion transporter 3 (OAT3), organic anion transporting polypeptides 1B1 and 1B3 (OATP1B1 & OATP1B3), and multidrug resistance-associated protein 2 (
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