CYCLOLAB Ltd.

About company

CycloLab as an SME focusing on cyclodextrin research and development for over 30 years. We are working in the fields of pharmaceutical, cosmetic and food industry and analytical applications of cyclodextrins.

CycloLab has four main activities:

1. Production of sulfobutylether beta-cyclodextrin (SBECD, Dexolve) in multiple ton scale under cGMP  based on an FDA-approved DMF as a potent general solubilizer and stabilizer, compatible with all administration forms.

2. CycloLab as a CRO for cyclodextrin related services:
• development of products (pharma, cosmetic, food,) – formulation development, optimization, characterization, in vitro bioequivalence studies.
• offering custom synthesis of cyclodextrins, fine-tailored for certain guest molecules or purposes,
• performing (sub)pilot-scale cGMP compliant manufacturing of cyclodextrins to be used as APIs or excipients in clinical studies or cyclodextrin enabled formulations for the same purpose
• all analytical tasks related to the above, under GMP (method development, validation, stability studies for formulation ingredients (APIs, cyclodextrins) and final products as well. In this aspect, we are deeply engaged with Sugammadex as well.

3. CycloLab offers the widest variety of cyclodextrins in various grades (pharma, standard, fine chemical) for various purposes (research, analytics, cell cultures, formulation studies, etc). Besides "regular" derivatives, we always develop specials: like maltooligomers, polymers or fluorescent-tagged products and Sugammadex related compounds.

4. As an R&D company, we develop next generation proprietary cyclodextrins and explore potential applications as well. These are focused in new areas like protein stabilization and non-viral gene delivery, fermentation and enzymatic processes, serum free culture media, creating selective and targeted drug delivery sytems.

  • HU
  • 2019
    On CPhI since
Contact info
Meet us at

CPhI Worldwide 2021

Fiera Milano, Milan, Italy
9-11 November 2021

Products from CYCLOLAB Ltd.

  • DIMEB

    Product DIMEB

    heptakis-2,6-dimethyl-beta-cyclodextrin
  • RAMEB

    Product RAMEB

    Methyl-beta-cyclodextrin
  • Methyl-beta-cyclodextrin

    Product Methyl-beta-cyclodextrin

    Methyl-beta-cyclodextrin
  • SGM

    Product SGM

    Sugammadex is one of the greatest successes in the history of cyclodextrins. There is an increasing interest for this product and for the development of Sugammadex since the approval by the FDA resulted in a 3-4-fold increase in the global sales of the product. SGM is used in anesthesia as an injectable antidote for rocuronium and similar NM blocking agents. 

    CycloLab has vast experience in the production of Per-6-halogen-gamma CD intermediates and has developed Sugammadex via various process routes and related compounds, supported by sensitive analytical tools to characterize the products.
    We provide: high purity standards (intermediates, Sugammadex, key process impurities), formulation development, optimization of API production...
  • HPBCD

    Product HPBCD

    hydroxypropyl beta cyclodextrin (EP, USP/NF)
  • Cyclodextrins

    Product Cyclodextrins

    cyclodextrin, sugammadex, sbecd, sulfobutyl, hydroxypropyl, HPBCD, HPGCD, ACD, BCD, GCD, betadex, alfadex, gammadex, formulation development
  • Dexolve

    Product Dexolve

    Dexolve is the first generic USP and EP-conform Betadex Sulfobutyl Ether Sodium for:• solubility enhancement (10 to 100,000 fold) • Improvement of chemical stability • Increased bioavailability, facilitated delivery • Reduced aggregation • Moderate irritationor reduced side-effects • Maximized safety, complete renal elimination • Enables formulation of water-insoluble APIs in all dosage forms • Lower API doses to be achieved • Maintained DMF TypeIV in US, Canada, China • Prepared via a self-developed proprietary, patented technology with a process independent from any existing patents • 48-month stability data • Successful production of over 150 subsequent USP compl. batches •  No down payment, No milestone payment, No royalty payment • Over 60 APIs in development using Dexolve
  • Hydroxypropyl beta cyclodextrin
  • Sugammadex

    Product Sugammadex

    Sugammadex is one of the greatest successes in the history of cyclodextrins. There is an increasing interest for this product and for the development of Sugammadex since the approval by the FDA resulted in a 3-4-fold increase in the global sales of the product. SGM is used in anesthesia as an injectable antidote for rocuronium and similar NM blocking agents. 

    CycloLab has vast experience in the production of Per-6-halogen-gamma CD intermediates and has developed Sugammadex via various process routes and related compounds, supported by sensitive analytical tools to characterize the products.
    We provide: high purity standards (intermediates, Sugammadex, key process impurities), formulation development, optimization of API production...
  • ACD

    Product ACD

    alfadex, alfa-cyclodextrin (EP, USP/NF)
  • alfa-cyclodextrin

CYCLOLAB Ltd. Resources