Improving Sub-Ambient Reaction Reproducibility

The DrySyn Snowstorm MULTI from Asynt provides a simple and highly effective way to perform multiple reactions in parallel across a large temperature range including sub-ambient chemistries such as organometallic syntheses and controlled rate crystallisation studies down to -60 °C.

Sub-ambient reactions have traditionally been difficult to undertake reproducibly on a small to medium scale. The DrySyn Snowstorm MULTI is able to accommodate up to 12 vials or three 100-mL round bottom flasks offering sub ambient reactions in parallel without the need for jacketed reaction vessels, or ice baths. Operating with a suitable chiller/circulator, a DrySyn SnowStorm MULTI provides accurate, stable temperature control down to -60 °C and up to +150 °C.

Being able to maintain a sub-ambient temperature, sometimes for significant periods, is important for reaction reproducibility. The DrySyn SnowStorm MULTI connects to an external chiller unit and holds temperatures at a set-point for as long as is required. Setting temperature ramping profiles is also possible on the DrySyn Snowstorm MULTI which is important in crystallisation studies.