New Single-Use Fermentor Brings Microbial Applications Up to Speed
A new single-use fermentor matches the performance of stainless steel while eliminating clean/steam-in-place steps, reducing set-up time and mitigating cross-contamination risk in microbial fermentation.
The Thermo Scientific HyPerforma Single-Use Fermentor (SUF) is the first single-use system specifically engineered for microbial fermentation and designed to scale up from the lab to GMP production. Capable of meeting the aggressive performance demands of industrial microbiology, the HyPerforma SUF integrates into existing Thermo Scientific single-use technologies to achieve exceptional efficiency and scalability across the entire bioprocessing workflow.
Thermo Fisher will showcase its new HyPerforma Single-Use Fermentor this week at the BioProcess International Conference and Exhibition, 21–23 October 2014 at the Hynes Convention Center, Booth #301.
“Until now, fermentation equipment has been hard to convert to single-use due to the aggressive demands of fast-growing microbial cultures. Modified single-use bioreactors have been used, but are not designed for ideal growth conditions,” said Daniel Nelson, product manager, single-use systems at Thermo Fisher Scientific. “Through engineering an innovative, single-use exhaust and condenser system, coupled with powerful mixing, we overcame constraints in oxygen transfer to create the first purpose-built single-use fermentor. The HyPerforma SUF is a natural progression developed specifically for fermentation processes and a dedicated tool needed to increase choice, flexibility and performance for all bioprocessing workflows.”
Key product features include:
• Effective mass transfer, powerful mixing, and temperature control using three Rushton-style impellers and baffled, jacketed vessel
• 5:1 turndown ratio and 3:1 height-to-diameter ratio for consistent scalability and flexibility of process design (both 30 L and 300 L models).
• Efficient exhaust management system, enabling high flow rates (2VVM)
• Vertical access door for easy loading and retrieval of the bioprocess containers and harvest lines.
• Turn-around times between batches as low as 2 hours.
As a two-part product, the HyPerforma SUF comes paired with a Thermo Scientific BioProcess Container (BPC) — pre-sterilised and gamma irradiated. With an open architecture design, the HyPerforma SUF with BPC is highly flexible. It can also be retrofitted into existing fermentor operations, as well as configured to operate with existing software and control equipment, or delivered turnkey for immediate use.
Related News
-
News Patients vs Pharma – who will the Inflation Reduction Act affect the most?
The Inflation Reduction Act brought in by the Biden administration in 2022 aims to give better and more equitable access to healthcare in the USA. However, pharma companies are now concerned about the other potential costs of such legislation. -
News CPHI Podcast Series: What does the changing US Pharma market mean for industry and patients alike?
In this week's episode of the CPHI Podcast Series Lucy Chard, Digital Editor for CPHI Online is joined by James Manser to discuss the political and market changes in the US pharma field. -
News CPHI Barcelona Annual Report illuminates industry trends for 2024
The CPHI Annual Survey comes into it’s 7th year to report on the predicted trends for 2024. Over 250 pharma executives were asked 35 questions, with their answers informing the industry landscape for the next year, spanning all major pharma marke... -
News Which 10 drugs are open to price negotiation with Medicare in the USA?
The Centres for Medicare & Medicaid Services, under the Biden administration in the USA, has released a list of the 10 drugs that will be open to price negotiations as part of the new legislation under the Inflation Reduction Act (IRA). -
News EU Medical Devices Regulation causes unintended disappearances of medical devices for children, doctors state
Doctor groups and associations have appealed to the EU to correct the EU Medical Devices Regulation law that may cause unintended shortages of essential drug and medical devices for children and rare disease patients. -
News 10 Major Drug Approvals So Far in 2023
Last year, 37 novel drugs were approved by the FDA, this was a high number for such a category, and covered many fields including oncology, demonstrating how promising further research is, and how it is only continuing to build. To date, there are alre... -
News Detecting Alzheimer's disease with a simple lateral flow test
A novel rapid diagnostic test for early-stage Alzheimer's disease has been developed using a biomarker binder from Aptamer Group along with technology from Neuro-Bio, the neurodegenerative disease experts. -
News CPHI Podcast Series: outsourcing and manufacturing trends
Listen to the CPHI Podcast Series this June to hear Gil Roth of the PBOA speak with Digital Editor Lucy Chard about the biggest trends and topics to watch in pharma outsourcing and manufacturing at the minute.
Position your company at the heart of the global Pharma industry with a CPHI Online membership
-
Your products and solutions visible to thousands of visitors within the largest Pharma marketplace
-
Generate high-quality, engaged leads for your business, all year round
-
Promote your business as the industry’s thought-leader by hosting your reports, brochures and videos within your profile
-
Your company’s profile boosted at all participating CPHI events
-
An easy-to-use platform with a detailed dashboard showing your leads and performance