Colorcon's breakthrough for direct compression

New starch-based excipient plays an important role in enhancing the stability of moisture-sensitive APIs.

In recent years, formulation scientists have become increasingly interested in direct compression (DC) tablet manufacturing processes. In response to this market trend, Colorcon has developed StarTab, Directly Compressible Starch. This represents a breakthrough for the DC process, where StarTab’s unique particle size and shape provides excellent flow and superior compressibility on high-speed compression machines; enabling formulation scientists to simplify tablet formulation and manufacturing. StarTab also plays an important role in enhancing the stability of moisture-sensitive active pharmaceutical ingredients.

Dr Ali Rajabi-Siahboomi, Chief Scientific Officer at Colorcon explains: “Through extensive market and scientific research using particle engineering, we designed StarTab to be used as a single ingredient for the direct compression process. As StarTab uses material that is accepted by regulatory bodies across the world; there are no barriers to adoption of the product.”

Jayesh Parmar, General Manager, Colorcon says: “The launch of this latest innovation meets the needs of the pharmaceutical industry for direct compression and is an advanced addition complementing the portfolio of solutions we provide through our starch product line.”