GASIL® Mesoporous Silicas – Elevating Pharmaceutical and Nutraceutical Excellence

Gasil® mesoporous silica gels address the core formulation challenges in pharmaceuticals and nutraceuticals — moisture sensitivity, liquid-to-powder conversion and dosing accuracy, poor powder flow for tableting, and low API solubility requiring amorphization.

In the pharmaceuticals and nutraceuticals sector, the quest for superior solid formulations is unending. Achieving them is a complex challenge. Formulations are mixtures of powders of different granulometry and hygroscopicity and liquids with different viscosity and hydrophilicity. Synthetic and natural ingredients and excipients like polymers are also often sensitive to moisture. Those that are liquid will render formulations sticky and affect their processability and require accurate dosing that can only be delivered in a dry form. The use of flow aids is essential to ensure solid actives flow well for tablet compaction. Many APIs have low solubility and require amorphization to enhance their solubility and effectiveness in vivo. Gasil® mesoporous silica gels provide solutions to many of the problems encountered in solid pharmaceutical and nutraceutical formulations.