NIH funds biobank to support Precision Medicine Initiative Cohort Program

$142 million will be awarded over 5 years to the Mayo Clinic to establish the world’s largest research-cohort biobank for the PMI Cohort Program, a longitudinal research study which aims to enroll 1 million or more US participants to advance precision medicine.

“This range of information at the scale of 1 million people will be an unprecedented resource for researchers working to understand all the factors that influence health and disease,” said NIH Director Francis S. Collins. “The more we understand about individual differences, the better able we will be to tailor the prevention and treatment of illness.”

The Mayo Clinic will provide the infrastructure to store, analyze and make available to researchers more than 35 million biospecimens and associated data using state-of-the-art laboratory automation and robotics for efficient processing and retrieval. Biobank staff will follow a detailed set of policies to safeguard the collection against contamination or loss and to protect participant confidentiality. Additionally, the Mayo Clinic Florida Biospecimen Accessioning and Processing Core laboratory site will provide sample storage for 20-25% (8-10 million samples) of the collection, in order to protect the national resource from a localized natural disaster.

Stephen N. Thibodeau, co-director of the Mayo Clinic Center for Individualized Medicine Biorepositories Program, and Mine Cicek, director of the Mayo Clinic Biospecimen Accessioning and Processing Core Laboratory, will oversee the biobank. Dr Thibodeau also will serve on the PMI Cohort Program Steering Committee to help guide the program’s plans and activities.

“This is an extraordinary opportunity for Mayo Clinic to participate with NIH and share our expertise in such an important national research initiative,” says Dr. Thibodeau. “We are delighted that our state-of-the-art facilities will serve as an active, vital research resource for the 1 million participant biospecimen collection. The Mayo Clinic Center for Individualized Medicine is committed to embracing the potential of precision medicine to improve healthcare.”

Later this summer, NIH will announce funding awards for the PMI Cohort Program Coordinating Center, Participant Technologies Center and Healthcare Provider Organization Enrollment Centers, in preparation for the program’s main launch later in 2016.