Captisol is a derivatized beta cyclodextrin used in 16 FDA-approved products to date, including VEKLURY® (remdesivir) and KYPROLIS®️ (carfilzomib) to help solubilize & stabilize difficult to deliver molecules. Made by CyDex Pharmaceuticals (a Ligand Company), Captisol is the leading pharmaceutical-grade sulfobutylether beta-cyclodextrin (SBECD), with an excellent record of safety and consistency.
Captisol has been used in therapeutics across many routes of administration, including parenteral, oral, subcutaneous, ophthalmic, nasal, inhalation, and dermal. It is prepared by an all-aqueous process and distributed world-wide. Increasingly, partners are also demonstrating the benefits of Captisol in consumer health, supplements, and personal care products.