Glicocholic Acid

Glicocholic Acid
Product Description

ICE Pharma produces Glycocholic Acid via chemical synthesis from high-purity cholic acid, ensuring consistency, traceability, and GMP-compatible quality. The final product is chemically identical to its natural counterpart and demonstrates excellent safety and biocompatibility in pharmaceutical applications. Our high-purity Glycocholic Acid is manufactured at ICE Pharma’s state-of-the-art facility in Italy, operating under stringent GMP standards. Each batch undergoes rigorous quality control to ensure high purity, consistency, and safety.

ICE S.p.A

  • Country/Region:
    Italy
  • On CPHI since:
    2015
  • Certificates:
    4
  • Employees:
    1000 - 4999
Company types
CMO/CDMO
Contract Service
Manufacturer/Innovator
Pharmaceutical company
Primary activities
API Producer
Contract Manufacturer
Excipients Manufacturer
Generic APIs producer
Intermediates Manufacturer
Nutraceuticals
Pharmaceutical Company (generic finished products)
Pharmaceutical Company (innovator finished products)
Specifications
  • CAS Registry Number
    475-31-0
  • Details
    Glycocholic Acid (GCA) is the glycine conjugate of cholic acid and one of the primary bile acid components in human bile. The amphiphilic nature of Glycocholic acid – meaning it has both hydrophilic and hydrophobic regions – making it ideal for micelle formation, fats and vitamins solubilisation and enhancing the bioavailability of poorly soluble drugs. Glycocholic acid can also regulate the microbiological activity by limiting bacterial growth.

    Applications

    - Injectable Drug Formulations: GCA is widely used in parenteral formulations due to its ability to form mixed micelles, improving solubility and stability of hydrophobic active ingredients and vitamins
    - Oral and Nasal Drug Delivery: As a bile acid excipient, GCA supports enhanced solubilization of poor soluble drugs, absorption and permeability across mucosal membranes, making it suitable for oral suspensions and nasal spray applications.

ICE S.p.A

  • Country/Region:
    Italy
  • On CPHI since:
    2015
  • Certificates:
    4
  • Employees:
    1000 - 4999
Company types
CMO/CDMO
Contract Service
Manufacturer/Innovator
Pharmaceutical company
Primary activities
API Producer
Contract Manufacturer
Excipients Manufacturer
Generic APIs producer
Intermediates Manufacturer
Nutraceuticals
Pharmaceutical Company (generic finished products)
Pharmaceutical Company (innovator finished products)

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ICE S.p.A resources (4)