Gutron (5 mg tablet)

Midodrine is a prodrug, i.e., the therapeutic effect of orally administered midodrine is due to and directly related to its conversion after absorption to desglymidodrine which differs chemically from methoxamine only by lacking a methyl group on the side chain. Midodrine hydrochloride is: 2-amino-N-[2-(2, 5-dimethoxyphenyl) -2-hydroxyethyl]- monohydrochloride, (±)-acetamide, or (±)-2-Amino-N-(N-hydroxy-2, 5-dimethoxyphenethyl) acetamide monohydrochloride. GUTRON is used to treat the symptoms of idiopathic orthostatic hypotension found in Bradbury-Eggleston or Shy-Drager syndromes. Idiopathic orthostatic hypotension is a fall in blood pressure that occurs upon rising abruptly to an upright position although it may also occur following a period of prolonged standing. The body's nervous system is responsible for this type of hypotension. GUTRON is administered in those cases where the response to other therapy is not adequate. GUTRON is also used where hypotension is a consequence of other medical disorders such as diabetes or Parkinson's disease. Hypotension is low blood pressure. It is a measure of the blood pressing on the artery walls. This pressure helps move your blood around your body. GUTRON (midodrine hydrochloride) is indicated to attenuate symptoms of chronic orthostatic hypotension due to autonomic failure in patients with Bradbury-Eggleston or Shy-Drager syndromes and other medical disorders such as diabetes mellitus or Parkinson's disease. GUTRON may increase your blood pressure by constricting the walls of your blood vessels. Presentation of Midodrine hydrochloride as 5 mg tablets: Orange, circular, flat tablets of 7 mm scored on one side and embossed GU above the score and 5,0 below the score. Packaging: 5 mg tablets/ 100 tablets. Storage: Keep tablets in the original container and protect from light until it is time to take them. Keep GUTRON tablets in a cool dry place where the temperature stays below 25°C.