Nifedipine

Nifedipine is a dihydropyridine calcium antagonist, which can inhibit the uptake of Ca2+ by myocardium and vascular smooth muscle, dilate coronary arteries, increase coronary artery blood flow, and improve myocardial tolerance to ischemia, and at the same time dilate the small peripheral arteries, reduce peripheral vascular resistance, relieve coronary artery spasm, increase coronary artery flow, and improve myocardial hypoxia, which can lead to the decrease of blood pressure. Small doses of coronary artery dilation does not affect blood pressure, for better anti-angina drugs. Used for the prevention and treatment of coronary angina, no adverse effect on respiratory function, especially for the Chemicalbook angina caused by coronary artery spasm and angina with respiratory tract obstructive disease is the best effect, and its efficacy is better than β-blockers. It is also indicated for all types of hypertension, including severe and refractory hypertension.