Paclitaxel

Paclitaxel
Product Description

Paclitaxel is a Cremophor-free, albumin-bound paclitaxel formulation where paclitaxel is delivered in a suspension of albumin nanoparticles. It is administered as a 30-minute IV infusion without steroid or antihistamine premedication. It eliminates the need for Cremophor EL solvent, thereby removing the risk of hypersensitivity reactions and the requirement for steroid or antihistamine premedication, while also reducing infusion time to just 30 minutes compared to 3 hours for conventional paclitaxel. The albumin-bound nanoparticle formulation leverages the gp60 albumin receptor pathway to enhance transcytosis and tumor penetration, achieving approximately 70% higher maximum tolerated dose than Cremophor-based paclitaxel.

QILU PHARMACEUTICAL CO., LTD.

  • Country/Region:
    China
  • On CPHI since:
    2015
  • Employees:
    5000+
Company types
Manufacturer/Innovator
Specifications

QILU PHARMACEUTICAL CO., LTD.

  • Country/Region:
    China
  • On CPHI since:
    2015
  • Employees:
    5000+
Company types
Manufacturer/Innovator

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